EP 1947938 A4 20090701 - MACROCYCLIC FORMULATIONS FOR TRANSMEMBRANE DRUG DELIVERY
Title (en)
MACROCYCLIC FORMULATIONS FOR TRANSMEMBRANE DRUG DELIVERY
Title (de)
MAKROCYCLISCHE FORMULIERUNGEN FÜR DIE TRANSMEMBRANALE ARZNEISTOFFABGABE
Title (fr)
FORMULATIONS MACROCYCLIQUES POUR L'ADMINISTRATION TRANSMEMBRANAIRE DE MEDICAMENT
Publication
Application
Priority
- US 2006042827 W 20061102
- US 26571105 A 20051102
Abstract (en)
[origin: WO2007056068A2] Topically applied pharmaceutical products comprising (a) an active ingredient, (b) an organogel, and (c) a non-irritating permeation enhancer, are disclosed, along with and methods of use and formulations thereof. The topically applied products and methods are intended to be used to enhance any of the transdermal, subdermal, transmembrane, musculoskeletal, transungual, transonychial, and / or peronychial deliveries of a therapeutically effective amount of an active ingredient to a patient. The invention is particularly directed to topically applied pharmaceutical products for enhancing the delivery of a therapeutically effective amount of an active ingredient to a diseased or infected nail bed, nail matrix, and / or nail plate in the toenails or fingernails of a patient suffering from onychomycosis. The invention is also directed to delivery of an anti-inflammatory agent, preferably of the Cox-2 enzyme inhibitory class, topically to a site of soft tissue injury or discomfort.
IPC 8 full level
A61K 9/06 (2006.01); A61K 31/137 (2006.01); A61K 31/4174 (2006.01); A61K 47/10 (2006.01); A61K 47/14 (2006.01); A61K 47/24 (2006.01)
CPC (source: EP)
A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 31/137 (2013.01); A61K 31/496 (2013.01)
Citation (search report)
- [XY] US 5837289 A 19981117 - GRASELA JOHN C [US], et al
- [X] WO 9606636 A1 19960307 - CRANDALL WILSON TRAFTON [US]
- [X] US 5945409 A 19990831 - CRANDALL WILSON TRAFTON [US]
- [X] US 5817699 A 19981006 - FLORES JOHN A [US], et al
- [X] WO 9511015 A1 19950427 - ELSON MELVIN L [US]
- [X] WO 9911208 A1 19990311 - WILLIAMS C DONALD [US], et al
- [Y] WO 0160325 A1 20010823 - BENTLEY PHARMACEUTICALS INC [US], et al
- [A] US 2005123592 A1 20050609 - GYURIK ROBERT J [US], et al
- See references of WO 2007056068A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007056068 A2 20070518; WO 2007056068 A3 20070927; EP 1947938 A2 20080730; EP 1947938 A4 20090701
DOCDB simple family (application)
US 2006042827 W 20061102; EP 06827385 A 20061102