EP 1948792 A1 20080730 - CONDITIONALLY REPLICATING VIRUSES AND METHODS FOR CANCER VIROTHERAPY
Title (en)
CONDITIONALLY REPLICATING VIRUSES AND METHODS FOR CANCER VIROTHERAPY
Title (de)
KONDITIONAL REPLIZIERENDE VIREN UND VERFAHREN ZUR KREBSVIROTHERAPIE
Title (fr)
REPRODUCTION CONDITIONNELLE DE VIRUS ET MÉTHODES POUR VIROTHÉRAPIE DE CANCERS
Publication
Application
Priority
US 2005038918 W 20051028
Abstract (en)
[origin: WO2007050074A1] The present invention provides for methods and compositions for translation of a viral vector both in vitro and in vivo. Specifically, the present invention pertains to a transnational control element placed in a vector to a cause a selective translation of a viral vector. In one embodiment, the present invention provides for methods and compositions for conditionally expressing a viral vector inside tumor cells, while leaving normal cells unaffected due to their inability to translate the vector.
IPC 8 full level
C12N 7/00 (2006.01); A61K 48/00 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 35/04 (2017.12); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2710/10043 (2013.01); C12N 2820/002 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007050074 A1 20070503; AU 2005337612 A1 20070503; AU 2005337612 A8 20080703; CA 2627638 A1 20070503; EP 1948792 A1 20080730; EP 1948792 A4 20100804; JP 2009513133 A 20090402
DOCDB simple family (application)
US 2005038918 W 20051028; AU 2005337612 A 20051028; CA 2627638 A 20051028; EP 05824940 A 20051028; JP 2008537668 A 20051028