EP 1953244 A1 20080806 - Cancer profiles

Title (en)

Cancer profiles

Title (de)

Krebsprofile

Title (fr)

Profils de cancer

Publication

EP 1953244 A1 20080806 (EN)

Application

EP 08007724 A 20030109

Priority

EP 03700442 A 20030109
US 34695202 P 20020109

Abstract (en)

The present invention relates to genetic profiles and markers of cancers and provides systems and methods for screening drugs that are effective for specific patients and types of cancers, in particular, the present invention provides personalized treatment customized to an individual's cancer.

IPC 8 full level

C12N 15/09 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01)

CPC (source: EP US)

C12Q 1/6883 (2013.01 - EP US); C12Q 1/6886 (2013.01 - EP US); C12Q 2539/10 (2013.01 - EP US); C12Q 2600/106 (2013.01 - EP US); C12Q 2600/136 (2013.01 - EP US); C12Q 2600/158 (2013.01 - EP US)

Citation (applicant)

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Citation (search report)

[X] WO 0039336 A1 20000706 - ROSETTA INPHARMATICS INC [US]
[YD] US 5846717 A 19981208 - BROW MARY ANN D [US], et al
[X] SCHERF U ET AL: "A gene expression database for the molecular pharmacology of cancer", NATURE GENETICS, NATURE AMERICA, NEW YORK, US, vol. 24, no. 3, 1 March 2000 (2000-03-01), pages 236 - 244, XP002224798, ISSN: 1061-4036
[X] STAUNTON J E ET AL: "Chemosensitivity prediction by transcriptional profiling", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 98, no. 19, 11 September 2001 (2001-09-11), pages 10787 - 10792, XP002224800, ISSN: 0027-8424
[PX] ZEMBUTSU H ET AL: "Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, vol. 62, no. 2, 15 January 2002 (2002-01-15), pages 518 - 527, XP002224797, ISSN: 0008-5472
[Y] UEYAMA YOSHITO ET AL: "In vivo chemosensitivity of human malignant cystosarcoma phyllodes xenografts.", ONCOLOGY REPORTS, vol. 7, no. 2, March 2000 (2000-03-01), pages 257 - 260, XP008021860, ISSN: 1021-335X
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[Y] HILSENBECK S G ET AL: "Statistical analysis of array expression data as applied to the problem of tamoxifen resistance.", JOURNAL OF THE NATIONAL CANCER INSTITUTE. UNITED STATES 3 MAR 1999, vol. 91, no. 5, 3 March 1999 (1999-03-03), pages 453 - 459, XP009002755, ISSN: 0027-8874
[Y] TAKECHI T ET AL: "Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells.", JAPANESE JOURNAL OF CANCER RESEARCH: GANN. JAPAN JUN 2001, vol. 92, no. 6, June 2001 (2001-06-01), pages 696 - 703, XP002254038, ISSN: 0910-5050
[Y] BEYER-SEHLMEYER G ET AL: "Suppressive subtractive hybridisation reveals differential expression of serglycin, sorcin, bone marrow proteoglycan and prostate-tumour-inducing gene I (PTI-1) in drug-resistant and sensitive tumour cell lines of haematopoetic origin.", EUROPEAN JOURNAL OF CANCER, vol. 35, no. 12, November 1999 (1999-11-01), pages 1735 - 1742, XP002254039, ISSN: 0959-8049
[Y] COLLIE-DUGUID E S R ET AL: "Cloning and initial characterization of the human DPYD gene promoter.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 271, no. 1, 29 April 2000 (2000-04-29), pages 28 - 35, XP002255521, ISSN: 0006-291X

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

Designated extension state (EPC)

AL LT LV MK RO

DOCDB simple family (publication)

WO 03057916 A2 20030717; WO 03057916 A3 20040422; AU 2003201741 A1 20030724; EP 1466016 A2 20041013; EP 1953244 A1 20080806; JP 2005532036 A 20051027; US 2003165954 A1 20030904

DOCDB simple family (application)

IB 0300360 W 20030109; AU 2003201741 A 20030109; EP 03700442 A 20030109; EP 08007724 A 20030109; JP 2003558209 A 20030109; US 33953303 A 20030109