Global Patent Index - EP 1963265 A1

EP 1963265 A1 20080903 - PROCESS FOR THE PREPARATION OF PERINDOPRIL AND SALTS THEREOF

Title (en)

PROCESS FOR THE PREPARATION OF PERINDOPRIL AND SALTS THEREOF

Title (de)

VERFAHREN ZUR HERSTELLUNG VON PERINDOPRIL UND SALZEN DAVON

Title (fr)

PROCEDE DE FABRICATION DE PERINDOPRIL ET DE SELS DE PERINDOPRIL

Publication

EP 1963265 A1 20080903 (EN)

Application

EP 06829234 A 20061201

Priority

  • EP 2006011558 W 20061201
  • EP 05026160 A 20051201
  • EP 06829234 A 20061201

Abstract (en)

[origin: EP1792896A1] The present invention relates to a process for the preparation of the ACE inhibitor (2S,3aS,7aS)-1-((2S)-2-(((1S)-1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-1H-indol-2-carboxylic acid and of pharmaceutically acceptable salts thereof as well as to processes for preparing a N-((S)-1-carbethoxybutyl)-(S)-alanine intermediate and a (2S,3aS,7aS)-octahydroindole-2-carboxylic acid intermediate in a purified form.

IPC 8 full level

C07D 209/42 (2006.01); C07C 227/40 (2006.01); C07C 227/42 (2006.01)

CPC (source: EP)

C07C 227/40 (2013.01); C07C 227/42 (2013.01); C07D 209/42 (2013.01)

Citation (search report)

See references of WO 2007062865A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

DOCDB simple family (publication)

EP 1792896 A1 20070606; EP 1963265 A1 20080903; WO 2007062865 A1 20070607

DOCDB simple family (application)

EP 05026160 A 20051201; EP 06829234 A 20061201; EP 2006011558 W 20061201