EP 1966239 A1 20080910 - OCTANOATE-REDUCED HUMAN ALBUMIN
Title (en)
OCTANOATE-REDUCED HUMAN ALBUMIN
Title (de)
OKTANOATREDUZIERTES HUMAN ALBUMIN
Title (fr)
ALBUMINE HUMAINE A TENEUR REDUITE EN OCTANOATE
Publication
Application
Priority
- EP 2006011970 W 20061213
- DE 102005062043 A 20051222
Abstract (en)
[origin: WO2007079886A1] The invention relates to the improvement of the transport properties of albumin which is produced on an industrial scale, e.g. via the Cohn process or by means of recombinant processes, and is mixed, during the production process, with substances that saturate the binding points on the albumin and thus affect the binding properties and transport properties of the final product. A special embodiment of the invention relates to pasteurized and then octanoate-reduced human albumin for therapeutic use, especially in a detoxification treatment of human plasma, e.g. for the intravenous treatment of acute or chronic liver diseases, and as a dialyzate in extracorporeal liver dialysis with albumin in the molecular adsorbent recirculating system (MARS) or in single-pass dialysis.
IPC 8 full level
C07K 14/765 (2006.01); A61K 38/38 (2006.01)
CPC (source: EP KR US)
A61K 38/38 (2013.01 - KR); A61P 1/16 (2017.12 - EP); A61P 7/08 (2017.12 - EP); A61P 7/10 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 39/02 (2017.12 - EP); A61P 39/04 (2017.12 - EP); C07K 14/765 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2007079886A1
Citation (examination)
- WO 2006120226 A1 20061116 - ALBUTEC GMBH [DE], et al
- COSTANTINO H R ET AL: "Heterogeneity of serum albumin samples with respect to solid-state aggregation via thiol-disulfide interchange -- Implications for sustained release from polymers", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 44, no. 2, 17 February 1997 (1997-02-17), pages 255 - 261, XP004015253, ISSN: 0168-3659, DOI: 10.1016/S0168-3659(96)01528-3
- KLAMMT S ET AL: "Albumin binding capacity (ABiC) is reduced in commercially available human serum albumin preparations with stabilizers", ZEITSCHRIFT FUER GASTROENTEROLOGIE, THIEME MEDICAL PUBLISHERS, DE, vol. 39, no. Suppl. 2, 1 June 2001 (2001-06-01), pages 24 - 27, XP009157590, ISSN: 0044-2771
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007079886 A1 20070719; AU 2006334795 A1 20070719; AU 2006334795 B2 20120216; CA 2634329 A1 20070719; EP 1966239 A1 20080910; JP 2009520714 A 20090528; JP 2012233007 A 20121129; KR 20080078010 A 20080826; US 2010168000 A1 20100701; US 2012238998 A1 20120920; US 8877711 B2 20141104
DOCDB simple family (application)
EP 2006011970 W 20061213; AU 2006334795 A 20061213; CA 2634329 A 20061213; EP 06829547 A 20061213; JP 2008546199 A 20061213; JP 2012187111 A 20120828; KR 20087015175 A 20080620; US 201213482897 A 20120529; US 8686706 A 20061213