EP 1969006 A2 20080917 - DETECTION OF HUMAN PLATELET ANTIGEN (HPA) ANTIBODIES
Title (en)
DETECTION OF HUMAN PLATELET ANTIGEN (HPA) ANTIBODIES
Title (de)
NACHWEIS VON ANTIKÖRPERN GEGEN DAS HUMAN PLATELET ANTIGEN (HPA)
Title (fr)
DETECTION D'ANTICORPS CONTRE UN ANTIGENE DE PLAQUETTES HUMAINES (HPA)
Publication
Application
Priority
- GB 2006004262 W 20061115
- GB 0523266 A 20051115
- GB 0611806 A 20060614
Abstract (en)
[origin: WO2007057665A2] Abstract This invention relates to recombinant GPIIIa molecules that lack the ligand binding A domain and bind to HPA-1 antibodies in monomeric form. These GPIIIa molecules can be recombinantly expressed at high levels and may be useful, for example, in the detection of HPA-1 antibodies. Such detection may be useful, for example, in the diagnosis and therapy of HPA antibody disorders such as Neonatal Alloimmune Immune Thrombocytpenia (NAIT), Post Transfusion Purpura (PTP) and Platelet Refractoriness (PR).
IPC 8 full level
C07K 14/705 (2006.01)
CPC (source: EP)
C07K 14/70557 (2013.01); G01N 33/6893 (2013.01); G01N 2800/222 (2013.01); G01N 2800/226 (2013.01)
Citation (search report)
See references of WO 2007057665A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007057665 A2 20070524; WO 2007057665 A3 20070802; EP 1969006 A2 20080917
DOCDB simple family (application)
GB 2006004262 W 20061115; EP 06808552 A 20061115