EP 1969368 A2 20080917 - POTENTIATION OF APOPTOSIS BY MONOCLONAL ANTIBODIES
Title (en)
POTENTIATION OF APOPTOSIS BY MONOCLONAL ANTIBODIES
Title (de)
POTENZIERUNG VON APOPTOSE DURCH MONOKLONALE ANTIKÖRPER
Title (fr)
POTENTIALISATION DE L' APOPTOSE PAR DES ANTICORPS MONOCLONAUX
Publication
Application
Priority
- FR 2006002767 W 20061215
- FR 0512815 A 20051216
Abstract (en)
[origin: CA2633331A1] The present invention relates to the use of a composition of anti-MLA-DR antibodies expressed in cell line YB210, the fucose content of which is less than 65%, for the in vitro induction of apoptosis.
IPC 8 full level
G01N 33/53 (2006.01); A61K 39/395 (2006.01); A61P 7/04 (2006.01); A61P 9/00 (2006.01); A61P 21/00 (2006.01); A61P 37/00 (2006.01); C07K 16/28 (2006.01); C12N 5/078 (2010.01); C12Q 1/00 (2006.01)
CPC (source: EP KR US)
A61P 7/00 (2018.01 - EP); A61P 7/04 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 21/00 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/04 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 16/2833 (2013.01 - EP KR US); C12N 5/0634 (2013.01 - EP KR US); C07K 2317/41 (2013.01 - EP KR US); C07K 2317/71 (2013.01 - EP KR US)
Citation (examination)
- DA SILVA ANTONIO J. ET AL: "Alefacept, an Immunomodulatory recombinant LFA-3/IgG1 fusion protein, induces CD16 signaling and CD2/CD16-dependent apoptosis of CD2+ cells", THE JOURNAL OF IMMUNOLOGY, vol. 168, 27 February 2002 (2002-02-27), pages 4462 - 4471
- DE ROMEUF CHRISTOPHE ET AL: "Chronic lymphocytic leukaemia cells are efficiently killed by an anti-CD20 monoclonal antibody selected for improved engagement of FcgammaRIIIA/CD16", BRITISH JOURNAL OF HAEMATOLOGY, vol. 140, 2008, pages 635 - 643
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2895086 A1 20070622; FR 2895086 B1 20121005; AU 2006328798 A1 20070628; AU 2006328798 B2 20120209; BR PI0619994 A2 20111025; CA 2633331 A1 20070628; CN 101375160 A 20090225; EP 1969368 A2 20080917; IL 192195 A0 20081229; JP 2009519302 A 20090514; KR 20080106164 A 20081204; US 2009305228 A1 20091210; WO 2007071839 A2 20070628; WO 2007071839 A3 20070823
DOCDB simple family (application)
FR 0512815 A 20051216; AU 2006328798 A 20061215; BR PI0619994 A 20061215; CA 2633331 A 20061215; CN 200680052923 A 20061215; EP 06841970 A 20061215; FR 2006002767 W 20061215; IL 19219508 A 20080615; JP 2008545047 A 20061215; KR 20087017266 A 20080715; US 9768606 A 20061215