EP 1970445 B1 20120926 - METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS
Title (en)
METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS
Title (de)
VERFAHREN ZUR NUKLEINSÄUREREPLIKATION UND NEUE KÜNSTLICHE BASENPAARE
Title (fr)
PROCÉDÉ POUR LA RÉPLICATION D'UN ACIDE NUCLÉIQUE ET NOUVELLE PAIRES DE BASES ARTIFICIELLES
Publication
Application
Priority
- JP 2006324484 W 20061207
- JP 2005356883 A 20051209
- JP 2006189806 A 20060710
Abstract (en)
[origin: EP1970445A1] The present invention relates to a method for nucleic acid replication and novel artificial base pairs. The method of the present invention for nucleic acid replication is characterized in that a deoxyribonucleoside 5'-triphosphate, in which the hydroxyl group of phosphoric acid at the ³-position is substituted with a group selected from the group consisting of an amino group, a methylamino group, a dimethylamino group, a mercapto group and a fluoro group, is used as a substrate during replication reaction. The novel artificial base pairs of the present invention are characterized in that 7-(2-thienyl)-imidazo[4,5-b]pyridine (Ds) or an analog thereof forms a base pair with pyrrole-2-carbaldehyde (Pa) or an analog thereof.
IPC 8 full level
C07H 21/00 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP KR US)
C07H 19/04 (2013.01 - EP US); C07H 19/044 (2013.01 - KR); C07H 21/00 (2013.01 - EP US); C07H 21/02 (2013.01 - KR); C07H 21/04 (2013.01 - KR); C12N 15/09 (2013.01 - KR); C12P 19/34 (2013.01 - EP US); C12Q 1/6844 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1970445 A1 20080917; EP 1970445 A4 20090729; EP 1970445 B1 20120926; AU 2006323745 A1 20070614; AU 2006323745 B2 20121122; CA 2642657 A1 20070614; CN 101365791 A 20090211; CN 101365791 B 20120725; HK 1121491 A1 20090424; JP 5146957 B2 20130220; JP WO2007066737 A1 20090521; KR 101404374 B1 20140609; KR 20080093986 A 20081022; US 2010036111 A1 20100211; US 8030478 B2 20111004; WO 2007066737 A1 20070614
DOCDB simple family (application)
EP 06834239 A 20061207; AU 2006323745 A 20061207; CA 2642657 A 20061207; CN 200680052596 A 20061207; HK 09101422 A 20090216; JP 2006324484 W 20061207; JP 2007549184 A 20061207; KR 20087016493 A 20061207; US 9651706 A 20061207