EP 1973142 A1 20080924 - Analysis of low molecular weight molecules by MALDI-MS
Title (en)
Analysis of low molecular weight molecules by MALDI-MS
Title (de)
Analyse von Molekülen mit geringem Molekulargewicht mittels MALDI-MS
Title (fr)
Analyse de molécules à faible poids moléculaire par MALDI-MS
Publication
Application
Priority
EP 07450051 A 20070320
Abstract (en)
The invention relates to a process for the analysis of molecules having a molecular weight of <1500 Da by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), wherein an analyte containing low molecular weight molecules is applied to a matrix material, which is characterized in that the matrix material comprises fullerene-derivatised silica. This process allows clear identification of small molecules through intensive signals without matrix-related background disturbances.
IPC 8 full level
H01J 49/16 (2006.01)
CPC (source: EP US)
H01J 49/0418 (2013.01 - EP US)
Citation (search report)
- [A] US 2005230615 A1 20051020 - FURUTANI HIROSHI [US], et al
- [A] US 2005277201 A1 20051215 - SIVARAJAN RAMESH [US], et al
- [Y] VALLANT, R.M., SZABO, Z., TROJER, L., NAJAM-UL-HAQ, M., RAINER, M., HUCK, C.W., BAKRY, R., BONN, G.K.: "A new analytical material-enhanced laser desorption ionization (MELDI) based approach for the determination of low-mass serum constituents using fullerene derivatives for selective enrichment", JOURNAL OF PROTEOME RESEARCH, vol. 6, 23 November 2006 (2006-11-23), pages 44 - 53, XP002444882
- [Y] GUMANOV L L ET AL: "Preparation and properties of sorbents based on silica gel containing covalently linked fullerene C60", RUSSIAN CHEMICAL BULLETIN, PLENUM PUBLISHING CO, NEW YORK, NY, US, vol. 45, no. 4, April 1996 (1996-04-01), pages 768, XP008081813, ISSN: 1066-5285
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
EP 1973142 A1 20080924; EP 2126958 A1 20091202; US 2010078572 A1 20100401; WO 2008113090 A1 20080925
DOCDB simple family (application)
EP 07450051 A 20070320; AT 2008000098 W 20080319; EP 08714295 A 20080319; US 53183208 A 20080319