EP 1973872 A4 20120509 - INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF
Title (en)
INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF
Title (de)
HISTONDEACETYLASE-HEMMER UND PROPHARMAKA DARAUS
Title (fr)
INHIBITEURS DE L'HISTONE DÉSACÉTYLASE ET PRO-MÉDICAMENTS À BASE DE CEUX-CI
Publication
Application
Priority
- CA 2007002260 W 20071219
- US 87076806 P 20061219
Abstract (en)
[origin: WO2008074132A1] The invention relates to the inhibition of histone deacetylase. The invention provides compounds, prodrugs thereof, and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
IPC 8 full level
A61K 31/10 (2006.01); A61K 31/16 (2006.01); A61K 31/17 (2006.01); A61K 31/18 (2006.01); A61K 31/34 (2006.01); A61K 31/381 (2006.01); A61K 31/433 (2006.01); A61K 31/435 (2006.01); A61P 35/00 (2006.01); C07C 259/10 (2006.01); C07C 275/42 (2006.01); C07C 311/21 (2006.01); C07C 317/44 (2006.01); C07D 285/135 (2006.01); C07D 307/54 (2006.01); C07D 333/34 (2006.01); C07D 333/62 (2006.01)
CPC (source: EP KR)
A61K 31/10 (2013.01 - KR); A61P 31/10 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 259/06 (2013.01 - EP); C07C 259/10 (2013.01 - EP); C07C 275/42 (2013.01 - EP); C07C 279/14 (2013.01 - EP); C07C 311/13 (2013.01 - EP); C07C 311/21 (2013.01 - EP); C07C 311/29 (2013.01 - EP); C07C 311/44 (2013.01 - EP); C07C 313/06 (2013.01 - EP); C07C 317/44 (2013.01 - EP); C07D 213/30 (2013.01 - EP); C07D 213/70 (2013.01 - EP); C07D 215/24 (2013.01 - EP); C07D 235/02 (2013.01 - EP); C07D 271/08 (2013.01 - EP); C07D 285/135 (2013.01 - EP); C07D 307/54 (2013.01 - KR); C07D 307/91 (2013.01 - EP); C07D 309/06 (2013.01 - EP); C07D 317/30 (2013.01 - EP); C07D 317/60 (2013.01 - EP); C07D 333/34 (2013.01 - EP); C07D 333/62 (2013.01 - EP KR); C07D 409/04 (2013.01 - EP); C07C 2601/02 (2017.04 - EP); C07C 2601/04 (2017.04 - EP)
Citation (search report)
- [X] DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; GUILLAUMEL, JEAN ET AL: "Synthesis of 3-chloroindolinones from variously substituted .beta.-nitrostyrenes", XP002672206, retrieved from STN Database accession no. 1981:424707 & GUILLAUMEL, JEAN ET AL: "Synthesis of 3-chloroindolinones from variously substituted .beta.-nitrostyrenes", JOURNAL OF HETEROCYCLIC CHEMISTRY , 17(7), 1531-6 CODEN: JHTCAD; ISSN: 0022-152X, 1980
- [X] DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ECKSTEIN, ZYGMUNT: "Synthesis of 6-methoxybenzoxazolone", XP002672207, retrieved from STN Database accession no. 1962:456227 & ECKSTEIN, ZYGMUNT: "Synthesis of 6-methoxybenzoxazolone", PRZEMYSL CHEMICZNY , 41(NO. 2), 66-8 CODEN: PRCHAB; ISSN: 0033-2496, 1962
- [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; DELIWALA, C. V. ET AL: "Chemotherapy of tuberculosis. V. Synthesis of some N4-acyl-N1-arylsulfanilhydroxamides", XP002672208, retrieved from STN Database accession no. 1951:36112 & DELIWALA, C. V. ET AL: "Chemotherapy of tuberculosis. V. Synthesis of some N4-acyl-N1-arylsulfanilhydroxamides", PROCEEDINGS - INDIAN ACADEMY OF SCIENCES, SECTION A , 31A, 183-6 CODEN: PISAA7; ISSN: 0370-0089, 1950
- [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; MOORE, MAURICE L. ET AL: "Substituted sulfanilamides. III. N4-Acyl-N1-hydroxy derivatives", XP002672209, retrieved from STN Database accession no. 1940:43200 & MOORE, MAURICE L. ET AL: "Substituted sulfanilamides. III. N4-Acyl-N1-hydroxy derivatives", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 62, 2097-9 CODEN: JACSAT; ISSN: 0002-7863, 1940
- [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; "Insecticidal N-benzoyl-N-pyridyloxyphenylureas", XP002672210, retrieved from STN Database accession no. 1986:5782 & JP S60112764 A 19850619 - ISHIHARA SANGYO KAISHA
- [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SAMIZO, FUMIO ET AL: "Preparation of benzothiazin-3-ones as matrix metalloprotease inhibitors and prodrugs for treatment of joint disease, cancer metastasis, inflammation and periodontitis", XP002672211, retrieved from STN Database accession no. 2002:344919 & JP 2002128769 A 20020509 - SUMITOMO PHARMA
- See references of WO 2008074132A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008074132 A1 20080626; AU 2007335216 A1 20080626; AU 2007335216 B2 20130815; AU 2007335216 C1 20140710; CA 2672192 A1 20080626; CN 101610996 A 20091223; EP 1973872 A1 20081001; EP 1973872 A4 20120509; EP 2573069 A2 20130327; EP 2573069 A3 20130522; JP 2010513326 A 20100430; JP 2014111615 A 20140619; KR 20090094383 A 20090904; MX 2009006542 A 20090630
DOCDB simple family (application)
CA 2007002260 W 20071219; AU 2007335216 A 20071219; CA 2672192 A 20071219; CN 200780051541 A 20071219; EP 07855542 A 20071219; EP 12191995 A 20071219; JP 2009541704 A 20071219; JP 2014006984 A 20140117; KR 20097015215 A 20071219; MX 2009006542 A 20071219