EP 1979357 A1 20081015 - SOLID FORMS OF A PYRROLOPYRIMIDINE DERIVATIVE AND THEIR USE AS ANTI-TUMOR AGENTS

Title (en)

SOLID FORMS OF A PYRROLOPYRIMIDINE DERIVATIVE AND THEIR USE AS ANTI-TUMOR AGENTS

Title (de)

FESTE FORMEN EINES PYRROLOPYRIMIDIN-DERIVATS UND IHRE VERWENDUNG ALS KREBSMITTEL

Title (fr)

FORMES SOLIDES D'UN DERIVE PYRROLOPYRIMIDINE ET LEUR UTILISATION ANTITUMORALE

Publication

EP 1979357 A1 20081015 (EN)

Application

EP 07704035 A 20070119

Priority

EP 2007050567 W 20070119
US 76122406 P 20060123

Abstract (en)

[origin: WO2007082946A1] The invention relates to new crystalline forms of {6-[4-{4-ethyl-piperazin-1 -ylmethyl)- phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1-phenyl-ethyl)-amine, the process for the preparation of these crystalline forms of {6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H- pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1 -phenyl-ethyl)-amine, compositions containing these crystalline forms of {6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d ]pyrimidin-4-yl}-((R)-1-phenyl-ethyl)-amine, and the use of these crystalline forms of {6-[4-(4-ethyl- piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-{(R)-1-phenyl-ethyl)-amine in diagnostic methods or therapeutic treatment of warm-blooded animals, especially humans.

IPC 8 full level

C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01)

CPC (source: EP KR)

A61K 31/519 (2013.01 - KR); A61P 35/00 (2017.12 - EP); C07D 487/04 (2013.01 - EP KR)

Citation (search report)

See references of WO 2007082946A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

DOCDB simple family (publication)

WO 2007082946 A1 20070726; AR 059090 A1 20080312; AU 2007206925 A1 20070726; BR PI0706729 A2 20110405; CA 2636954 A1 20070726; CN 101370814 A 20090218; EP 1979357 A1 20081015; JP 2009523768 A 20090625; KR 20080095859 A 20081029; PE 20071323 A1 20080215; RU 2008134314 A 20100227; TN SN08312 A1 20091229; TW 200738719 A 20071016

DOCDB simple family (application)

EP 2007050567 W 20070119; AR P070100240 A 20070119; AU 2007206925 A 20070119; BR PI0706729 A 20070119; CA 2636954 A 20070119; CN 200780002265 A 20070119; EP 07704035 A 20070119; JP 2008550775 A 20070119; KR 20087017912 A 20080722; PE 2007000072 A 20070123; RU 2008134314 A 20070119; TN SN08312 A 20080722; TW 96102341 A 20070122