EP 1985230 A1 20081029 - Method for filtering out artefacts of deep brain stimulation
Title (en)
Method for filtering out artefacts of deep brain stimulation
Title (de)
Verfahren zur Ausfilterung von Artefakten aus einer tiefen Hirnstimulation
Title (fr)
Procédé pour le filtrage d'artefacts de la stimulation cérébrale profonde
Publication
Application
Priority
EP 07300991 A 20070426
Abstract (en)
The present invention relates to a method for filtering the signal of neuronal activity during a high frequency deep brain stimulation (DBS) to remove the stimulus artefact in the observed signal, comprising the step of approximating the observed signal trajectories in phase space the observed signal being considered as a sum of the stimulation artefacts induced by the signal of stimulation, wherein the signal of stimulation is assumed to be a solution of an ordinary differential equation including a self-oscillating system with stable limit cycle; slicing the observed signal and its derivative into segments, each segment corresponding to a period of stimulation ; collecting N selected periods of stimulation to a training set ; estimating the limit cycle of the self-oscillating system ; synchronizing each artefact of the observed signal with the estimated limit cycle ; subtracting the estimated limit cycle from each artefact in phase space according to the synchronization ; collecting all segments in order to obtain whole filtered signal and finally presenting the results in time domain.
IPC 8 full level
CPC (source: EP US)
A61B 5/24 (2021.01 - EP US); A61B 5/7239 (2013.01 - EP US); A61B 5/291 (2021.01 - EP US); A61N 1/36082 (2013.01 - EP US)
Citation (search report)
- [A] US 6529774 B1 20030304 - GREENE DAVID A [US]
- [A] US 2006167369 A1 20060727 - MONTGOMERY ERWIN B JR [US], et al
- [A] US 2006149337 A1 20060706 - JOHN MICHAEL S [US]
- [A] US 2005119703 A1 20050602 - DILORENZO DANIEL J [US]
- [AD] HASHIMOTO TAKAO ET AL: "Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons", JOURNAL OF NEUROSCIENCE, NEW YORK, NY, US, vol. 23, no. 5, 1 March 2003 (2003-03-01), pages 1916 - 1923, XP007902895, ISSN: 0270-6474
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
EP 1985230 A1 20081029; EP 2139389 A1 20100106; EP 2139389 B1 20131211; JP 2010524612 A 20100722; JP 5282081 B2 20130904; US 2010185257 A1 20100722; US 8620420 B2 20131231; WO 2008132136 A1 20081106
DOCDB simple family (application)
EP 07300991 A 20070426; EP 08736546 A 20080424; EP 2008055012 W 20080424; JP 2010504691 A 20080424; US 59719608 A 20080424