EP 1986690 A2 20081105 - ANTI-FcRn ANTIBODIES FOR TREATEMENT OF AUTO/ALLO IMMUNE CONDITIONS
Title (en)
ANTI-FcRn ANTIBODIES FOR TREATEMENT OF AUTO/ALLO IMMUNE CONDITIONS
Title (de)
ANTIKÖRPER GEGEN FCRN ZUR BEHANDLUNG VON AUTO-/ALLOIMMUNLEIDEN
Title (fr)
ANTICORPS ANTI-FcRn UTILISES DANS LE TRAITEMENT D'ETATS AUTO/ALLO-IMMUNS
Publication
Application
Priority
- US 2007001742 W 20070123
- US 76215106 P 20060125
- US 63467606 A 20061206
Abstract (en)
[origin: WO2007087289A2] Antibodies to heavy chain of human FcRn are provided which function as non- competitive inhibitors of IgG binding to FcRn. The antibodies may be polyclonal, monoclonal, chimeric or humanized, or antigen binding fragments thereof. These antibodies are useful for reducing the concentration of pathogenic IgGs in individuals and therefore used as a therapeutic tool in autoimmune and alloimmune conditions.
IPC 8 full level
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); G01N 33/563 (2006.01); G01N 33/564 (2006.01); G01N 33/577 (2006.01)
CPC (source: EP)
A61P 7/04 (2017.12); A61P 11/00 (2017.12); A61P 17/00 (2017.12); A61P 21/04 (2017.12); A61P 25/00 (2017.12); C07K 16/283 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007087289 A2 20070802; WO 2007087289 A3 20081009; CA 2637929 A1 20070802; EP 1986690 A2 20081105; EP 1986690 A4 20090513; JP 2009524664 A 20090702
DOCDB simple family (application)
US 2007001742 W 20070123; CA 2637929 A 20070123; EP 07762598 A 20070123; JP 2008552358 A 20070123