Global Patent Index - EP 1998779 A2

EP 1998779 A2 20081210 - USE OF (3S)-N-HYDROXY-4-({4-Ý(4-HYDROXY-2-BUTYNYL)OXY]PHENYL}SULFONYL)-2,2-DIMETHYL-3-THIOMORPHOLINE CARBOXAMIDE OR (S)-N-HYDROXY-4-(4-BUT-2-YNYLOXY-BENZENESULFONYL) -2,2-DIMETHYL-THIOMORPHOLINE -3-CARBOXAMIDE FOR TREATING INFLAMMATORY SKIN PATHOLOGIES

Title (en)

USE OF (3S)-N-HYDROXY-4-({4-Ý(4-HYDROXY-2-BUTYNYL)OXY]PHENYL}SULFONYL)-2,2-DIMETHYL-3-THIOMORPHOLINE CARBOXAMIDE OR (S)-N-HYDROXY-4-(4-BUT-2-YNYLOXY-BENZENESULFONYL) -2,2-DIMETHYL-THIOMORPHOLINE -3-CARBOXAMIDE FOR TREATING INFLAMMATORY SKIN PATHOLOGIES

Title (de)

VERWENDUNG VON (3S)-N-HYDROXY-4-({4-¦(4-HYDROXY-2-BUTYNYL)OXY]PHENYL}SULFONYL)-2,2-DIMETHYL-3-THIOMORPHOLIN-CARBOXAMID BZW. (S)-N-HYDROXY-4-(4-BUT-2-YNYLOXY-BENZOLSULFONYL) -2,2-DIMETHYL-THIOMORPHOLIN-3-CARBOXAMID ZUR BEHANDLUNG ENTZÜNDLICHER HAUTKRANKHEITEN

Title (fr)

UTILISATION DU (3S)-N-HYDROXY-4-({4-Ý(4-HYDROXY-2-BUTYNYL)OXY]PHÉNYL}SULFONYL)-2,2-DIMÉTHYL-3-THIOMORPHOLINE CARBOXAMIDE OU DU (S)-N-HYDROXY-4-(4-BUT-2-YNYLOXY-BENZENESULFONYL) -2,2-DIMETHYL-THIOMORPHOLINE -3-CARBOXAMIDE DANS LE TRAITEMENT DE PATHOLOGIES INFLAMMATOIRES CUTANÉES

Publication

EP 1998779 A2 20081210 (FR)

Application

EP 07731755 A 20070316

Priority

  • FR 2007050939 W 20070316
  • FR 0602429 A 20060320

Abstract (en)

[origin: WO2007107663A2] The invention relates to the use of a compound of formula (I) wherein R corresponds to a -CH3 radical or a CH<SUB>2</SUB>OH radical, or a pharmaceutically acceptable salt, pharmaceutically acceptable solvate or hydrate thereof, for preparing a medicament for preventing and/or treating inflammatory skin pathologies. The invention more precisely relates to the use of (3S)-N-hydroxy-4-({4-[(4- hydroxy-2-butynyl)oxy]phenyl}sulfonyl)-2,2-dimethyl-3-thiomorpholine carboxamide (or apratastat) or (S)-N-hydroxy-4-(4-but-2-ynyloxy-benzenesulfonyl)-2,2-dimethyl-thiomorpholine-3-carboxamide, or a pharmaceutically acceptable salt, pharmaceutically acceptable solvent or hydrate thereof, for preparating a medicament for preventing and/or treating inflammatory skin pathologies.

IPC 8 full level

A61K 31/54 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01); A61P 29/00 (2006.01)

CPC (source: EP US)

A61K 31/54 (2013.01 - EP US); A61P 17/00 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 29/00 (2017.12 - EP)

Citation (search report)

See references of WO 2007107663A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

FR 2898497 A1 20070921; FR 2898497 B1 20080516; CA 2645327 A1 20070927; EP 1998779 A2 20081210; US 2009137569 A1 20090528; WO 2007107663 A2 20070927; WO 2007107663 A3 20071122

DOCDB simple family (application)

FR 0602429 A 20060320; CA 2645327 A 20070316; EP 07731755 A 20070316; FR 2007050939 W 20070316; US 23245608 A 20080917