EP 2001458 B1 20100811 - USE OF VALPROIC ACID FOR THE TOPICAL TREATMENT OF MILD TO MODERATE ACNE VULGARIS
Title (en)
USE OF VALPROIC ACID FOR THE TOPICAL TREATMENT OF MILD TO MODERATE ACNE VULGARIS
Title (de)
VERWENDUNG VON VALPROINSÄURE ZUR TOPISCHEN BEHANDLUNG VON LEICHTER BIS MITTELSCHWERER AKNE VULGARIS
Title (fr)
UTILISATION D'ACIDE VALPROÏQUE POUR LE TRAITEMENT TOPIQUE D'ACNÉ VULGAIRE FAIBLE À MOYENNE
Publication
Application
Priority
- EP 2007002201 W 20070313
- EP 06006847 A 20060331
- EP 07711939 A 20070313
Abstract (en)
[origin: EP1839656A1] The present invention provides a surprising therapeutic beneficial use for the topical application of valproic acid as a single agent therapy for patients suffering from mild to moderate acne vulgaris. Topically applied VPA has a clinical efficacy comparable to that of the marketed standard medication for this indication, isotretinoin. Furthermore, topically applied VPA is on average well to very well tolerated. The invention relates to the topical medical use of VPA for the treatment of acne vulgaris and comprises the topical application of VPA or of a pharmaceutically acceptable salt thereof.
IPC 8 full level
A61K 31/19 (2006.01); A61P 17/10 (2006.01)
CPC (source: EP US)
A61K 31/19 (2013.01 - EP US); A61P 17/00 (2017.12 - EP); A61P 17/10 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1839656 A1 20071003; AT E476972 T1 20100815; DE 602007008385 D1 20100923; EP 2001458 A1 20081217; EP 2001458 B1 20100811; JP 2009534306 A 20090924; US 2009186809 A1 20090723; WO 2007112832 A1 20071011
DOCDB simple family (application)
EP 06006847 A 20060331; AT 07711939 T 20070313; DE 602007008385 T 20070313; EP 07711939 A 20070313; EP 2007002201 W 20070313; JP 2009501893 A 20070313; US 29535907 A 20070313