EP 2007721 B1 20110727 - A PROCESS FOR THE PURIFICATION OF ROPINIROLE HYDROCHLORIDE
Title (en)
A PROCESS FOR THE PURIFICATION OF ROPINIROLE HYDROCHLORIDE
Title (de)
VERFAHREN ZUR AUFREINIGUNG VON ROPINIROLHYDROCHLORID
Title (fr)
PROCÉDÉ DE PURIFICATION DU CHLORHYDRATE DE ROPINIROLE
Publication
Application
Priority
- IN 2007000116 W 20070321
- IN 476MU2006 A 20060329
Abstract (en)
[origin: WO2007110879A2] The present invention provides an improved process for the purification of Ropinirole hydrochloride of formula (Ia) comprising steps of: (i) dissolving Ropinirole hydrochloride in water; (ii) treating the solution obtained in step (i) with sodium dithionate and charcoal; (iii) treating the filtrate obtained in step (ii) with water immiscible solvent and base and isolating the free base; (iv) treating the free base obtained in step (iii) with ethanolic HCl to give Ropinirole hydrochloride.
IPC 8 full level
C07D 209/34 (2006.01)
CPC (source: EP US)
C07D 209/34 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007110879 A2 20071004; WO 2007110879 A3 20080117; AT E517865 T1 20110815; BR PI0709184 A2 20110628; CA 2645599 A1 20071004; EP 2007721 A2 20081231; EP 2007721 B1 20110727; US 2010249433 A1 20100930; US 7968731 B2 20110628; ZA 200809282 B 20091230
DOCDB simple family (application)
IN 2007000116 W 20070321; AT 07736576 T 20070321; BR PI0709184 A 20070321; CA 2645599 A 20070321; EP 07736576 A 20070321; US 29500307 A 20070321; ZA 200809282 A 20070321