Global Patent Index - EP 2010203 A2

EP 2010203 A2 20090107 - MACROCYCLIC PEPTIDES AND METHODS FOR MAKING AND USING THEM

Title (en)

MACROCYCLIC PEPTIDES AND METHODS FOR MAKING AND USING THEM

Title (de)

MAKROCYCLISCHE PEPTIDE SOWIE VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG

Title (fr)

PEPTIDES MACROCYCLIQUES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION

Publication

EP 2010203 A2 20090107 (EN)

Application

EP 07758829 A 20070319

Priority

  • US 2007064317 W 20070319
  • US 78329806 P 20060317
  • US 79711106 P 20060502
  • US 43637806 A 20060517

Abstract (en)

[origin: WO2007109620A2] The invention provides novel macrocyclic peptides and methods for their preparation. The invention also provides pharmaceutical compositions and methods to treat, prevent or ameliorate a cell proliferative disease or conditions, e.g., a cancer, in a subject in need thereof, including but not limited to a colon cancer, such as MSS or MSI colon cancer, and pancreatic cancer. This invention provides for the synthesis and development of novel anticancer agents that are based on the core structure Sansalvamide A (San A).

IPC 8 full level

A61K 38/12 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01)

CPC (source: EP)

C07K 7/64 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 2007109620A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

DOCDB simple family (publication)

WO 2007109620 A2 20070927; WO 2007109620 A3 20080110; EP 2010203 A2 20090107

DOCDB simple family (application)

US 2007064317 W 20070319; EP 07758829 A 20070319