EP 2012753 A2 20090114 - PROCESS FOR THE PRECIPITATION AND ISOLATION OF 6,6-DIMETHYL-3-AZA-BICYCLO [3.1.0]HEXANE-AMIDE COMPOUNDS BY CONTROLLED PRECIPITATION AND PHARMACEUTICAL FORMULATIONS CONTAINING SAME
Title (en)
PROCESS FOR THE PRECIPITATION AND ISOLATION OF 6,6-DIMETHYL-3-AZA-BICYCLO [3.1.0]HEXANE-AMIDE COMPOUNDS BY CONTROLLED PRECIPITATION AND PHARMACEUTICAL FORMULATIONS CONTAINING SAME
Title (de)
VERFAHREN ZUR AUSSCHEIDUNG UND ISOLIERUNG VON 6,6-DIMETHYL-3-AZA-BICYCLO [3.1.0]HEXAN-AMID-VERBINDUNGEN DURCH KONTROLLIERTE AUSSCHEIDUNG UND PHARMAZEUTISCHE FORMULIERUNGEN DAMIT
Title (fr)
PROCÉDÉ DE PRÉCIPITATION ET D'ISOLEMENT DE 6,6-DIMÉTHYL-3-AZA-BICYCLO[3.1.0]HEXANE-AMIDES PAR PRÉCIPITATION CONTRÔLÉE ET FORMULES PHARMACEUTIQUES LES CONTENANT
Publication
Application
Priority
- US 2007010255 W 20070426
- US 79575306 P 20060428
- US 79649006 P 20060501
- US 79671706 P 20060502
- US 87387706 P 20061207
Abstract (en)
[origin: WO2007127380A2] The present invention provides a method of continuous precipitation and isolation of an amorphous solid particulate form of 3-[2-(3-tert-Butyl-ureido)-3,3-dimethyl-butyryl]-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-2-carboxylic acid (2-carbamoyl-1-cyclobutylmethyl-2-oxo-ethyl)-amide having controlled physical properties. The present invention provides also pharmaceutical formulations comprising the precipitated compound.
IPC 8 full level
A61K 9/14 (2006.01)
CPC (source: EP US)
A61K 9/1623 (2013.01 - EP US); A61K 9/1652 (2013.01 - EP US); A61P 31/14 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 2007127380A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007127380 A2 20071108; WO 2007127380 A3 20080522; AR 060733 A1 20080710; CA 2650395 A1 20071108; EP 2012753 A2 20090114; JP 2009535345 A 20091001; JP 5592647 B2 20140917; PE 20080250 A1 20080410; SG 172690 A1 20110728; SG 172700 A1 20110728; US 2008193518 A1 20080814
DOCDB simple family (application)
US 2007010255 W 20070426; AR P070101875 A 20070430; CA 2650395 A 20070426; EP 07776356 A 20070426; JP 2009507824 A 20070426; PE 2007000535 A 20070502; SG 2011041902 A 20070426; SG 2011042884 A 20070426; US 78991507 A 20070426