EP 2019688 A2 20090204 - USE OF CATHEPSIN K ANTAGONISTS IN BONE PRODUCTION
Title (en)
USE OF CATHEPSIN K ANTAGONISTS IN BONE PRODUCTION
Title (de)
VERWENDUNG VON CATHEPSIN-K-ANTAGONISTEN BEI DER KNOCHENHERSTELLUNG
Title (fr)
UTILISATION D'ANTAGONISTES DE LA CATHEPSINE K DANS LA PRODUCTION OSSEUSE
Publication
Application
Priority
- US 2007069211 W 20070518
- US 74788606 P 20060522
- US 81045606 P 20060601
Abstract (en)
[origin: WO2007137149A2] The invention regards the modulation of a proteolytic enzyme, Cathepsin K that results in increased bone production by bone-forming cells. Drugs that target this enzyme within bone forming cells and inhibit its activity represent a new class of anabolic, or bone building, therapies. Such drugs are useful in the treatment of diseases or disorders such as osteoporosis, Paget' s disease, metastatic bone cancer, bone fractures, etc.
IPC 8 full level
A61K 39/395 (2006.01); A61K 31/70 (2006.01); A61K 38/00 (2006.01); C12N 5/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01)
CPC (source: EP)
A61K 31/336 (2013.01); A61P 1/02 (2017.12); A61P 19/00 (2017.12); A61P 19/08 (2017.12); A61P 19/10 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C12N 15/1137 (2013.01); C12Y 304/22038 (2013.01); G01N 33/6893 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); G01N 2333/8139 (2013.01); G01N 2333/96466 (2013.01); G01N 2500/00 (2013.01); G01N 2800/10 (2013.01)
Citation (search report)
See references of WO 2007137149A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007137149 A2 20071129; WO 2007137149 A3 20080214; AU 2007253796 A1 20071129; CA 2652600 A1 20071129; EP 2019688 A2 20090204; JP 2010503610 A 20100204
DOCDB simple family (application)
US 2007069211 W 20070518; AU 2007253796 A 20070518; CA 2652600 A 20070518; EP 07797567 A 20070518; JP 2009512230 A 20070518