Global Patent Index - EP 2019688 A2

EP 2019688 A2 2009-02-04 - USE OF CATHEPSIN K ANTAGONISTS IN BONE PRODUCTION

Title (en)

USE OF CATHEPSIN K ANTAGONISTS IN BONE PRODUCTION

Title (de)

VERWENDUNG VON CATHEPSIN-K-ANTAGONISTEN BEI DER KNOCHENHERSTELLUNG

Title (fr)

UTILISATION D'ANTAGONISTES DE LA CATHEPSINE K DANS LA PRODUCTION OSSEUSE

Publication

EP 2019688 A2 (EN)

Application

EP 07797567 A

Priority

  • US 2007069211 W
  • US 74788606 P
  • US 81045606 P

Abstract (en)

[origin: WO2007137149A2] The invention regards the modulation of a proteolytic enzyme, Cathepsin K that results in increased bone production by bone-forming cells. Drugs that target this enzyme within bone forming cells and inhibit its activity represent a new class of anabolic, or bone building, therapies. Such drugs are useful in the treatment of diseases or disorders such as osteoporosis, Paget' s disease, metastatic bone cancer, bone fractures, etc.

IPC 8 full level (invention and additional information)

A61K 39/395 (2006.01); A61K 31/70 (2006.01); A61K 38/00 (2006.01); C12N 5/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01)

CPC (invention and additional information)

G01N 33/6893 (2013.01); A61K 31/336 (2013.01); C12N 15/1137 (2013.01); C12Y 304/22038 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); G01N 2333/8139 (2013.01); G01N 2333/96466 (2013.01); G01N 2500/00 (2013.01); G01N 2800/10 (2013.01)

Citation (search report)

See references of WO 2007137149A3

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

EPO simple patent family

WO 2007137149 A2 20071129; WO 2007137149 A3 20080214; AU 2007253796 A1 20071129; CA 2652600 A1 20071129; EP 2019688 A2 20090204; JP 2010503610 A 20100204

INPADOC legal status


2011-07-06 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20101201

2009-08-26 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) (DELETED)

2009-02-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20081126

2009-02-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

2009-02-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Countries: AL BA HR MK RS