EP 2020993 A2 20090211 - SOLID PHARMACEUTICAL COMPOSITION OF GABAPENTIN
Title (en)
SOLID PHARMACEUTICAL COMPOSITION OF GABAPENTIN
Title (de)
FESTE PHARMAZEUTISCHE GABAPENTIN-ZUSAMMENSETZUNG
Title (fr)
COMPOSITION PHARMACEUTIQUE SOLIDE DE GABAPENTINE
Publication
Application
Priority
- EP 2007003914 W 20070503
- ES 200601164 A 20060508
Abstract (en)
[origin: WO2007128495A2] The present invention relates to solid pharmaceutical compositions of gabapentin that have good stability and good bioavailability of the active principle, and that can be used for preparing pharmaceutical solid forms of gabapentin for oral administration. The pharmaceutical composition of the invention is a solid composition comprising an intragranular phase and an extragranular phase. It is a solid composition that is of a granular appearance, but includes non-granulated particles of the extragranular phase. The invention lays on the incorporation of a hydrophobic compound in the intragranular phase, and a humsctant in the extragranular phase which leads to the preparation of solid compositions of gabapentin that have good stability and good bioavailability of the gabapentin.
IPC 8 full level
A61K 9/20 (2006.01); A61K 31/195 (2006.01)
CPC (source: EP ES)
A61K 9/2013 (2013.01 - EP); A61K 9/2054 (2013.01 - EP); A61K 31/195 (2013.01 - EP ES); A61P 25/08 (2017.12 - EP)
Citation (search report)
See references of WO 2007128495A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007128495 A2 20071115; WO 2007128495 A3 20080502; AR 060869 A1 20080716; EP 2020993 A2 20090211; ES 2288117 A1 20071216; ES 2288117 B1 20081201
DOCDB simple family (application)
EP 2007003914 W 20070503; AR P070101988 A 20070508; EP 07785797 A 20070503; ES 200601164 A 20060508