EP 2021474 A2 20090211 - RAGE FUSION PROTEINS, FORMULATIONS, AND METHODS OF USE THEREOF
Title (en)
RAGE FUSION PROTEINS, FORMULATIONS, AND METHODS OF USE THEREOF
Title (de)
RAGE-FUSIONSPROTEINE, FORMULIERUNGEN DARAUS UND VERFAHREN ZU IHRER VERWENDUNG
Title (fr)
PROTÉINES DE FUSION RAGE, FORMULATIONS ET LEURS PROCÉDÉS D'UTILISATION
Publication
Application
Priority
- US 2007010125 W 20070425
- US 79845506 P 20060505
Abstract (en)
[origin: WO2007130302A2] Disclosed are RAGE fusion proteins comprising RAGE polypeptide sequences linked to a second, non-RAGE polypeptide. The RAGE fusion protein may utilize a RAGE polypeptide domain comprising a RAGE ligand binding site and an interdomain linker directly linked to the N-terminus of an immunoglobulin C<SUB>H</SUB>2 domain. Also disclosed are RAGE fusion protein formulations and the use of the RAGE fusion proteins and RAGE fusion protein formulations as therapeutics for RAGE-mediated pathologies.
IPC 8 full level
C12N 15/13 (2006.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); C07K 16/00 (2006.01); C12N 15/62 (2006.01)
CPC (source: EP KR US)
A61P 1/04 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 9/14 (2018.01 - EP); A61P 11/02 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 17/06 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/04 (2018.01 - EP); A61P 37/06 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/70503 (2013.01 - EP US); C07K 19/00 (2013.01 - KR); C12N 15/09 (2013.01 - KR); C12N 15/62 (2013.01 - EP KR US); A61K 38/00 (2013.01 - EP US); C07K 2319/30 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007130302 A2 20071115; WO 2007130302 A3 20080403; AR 060862 A1 20080716; AU 2007248784 A1 20071115; AU 2007248784 B2 20131121; BR PI0711193 A2 20130618; CA 2651348 A1 20071115; CN 101548012 A 20090930; DO P2007000089 A 20071115; EA 017291 B1 20121130; EA 200870502 A1 20090630; EP 2021474 A2 20090211; EP 2380983 A2 20111026; EP 2380983 A3 20121205; IL 194482 A0 20110801; JP 2009536201 A 20091008; JP 5558810 B2 20140723; KR 20090008459 A 20090121; MX 2008013863 A 20081114; NL 2000626 A1 20071106; NZ 571692 A 20120112; PE 20080397 A1 20080428; SG 171670 A1 20110629; TW 200801036 A 20080101; US 2008045455 A1 20080221; US 2011282035 A1 20111117; US 7981424 B2 20110719; US 8344120 B2 20130101; UY 30324 A1 20080102; ZA 200809394 B 20090729
DOCDB simple family (application)
US 2007010125 W 20070425; AR P070101949 A 20070504; AU 2007248784 A 20070425; BR PI0711193 A 20070425; CA 2651348 A 20070425; CN 200780018207 A 20070425; DO 2007000089 A 20070504; EA 200870502 A 20070425; EP 07794379 A 20070425; EP 11167432 A 20070425; IL 19448208 A 20081002; JP 2009509615 A 20070425; KR 20087029731 A 20081204; MX 2008013863 A 20070425; NL 2000626 A 20070504; NZ 57169207 A 20070425; PE 2007000550 A 20070504; SG 2011032968 A 20070425; TW 96115905 A 20070504; US 201113158748 A 20110613; US 78963707 A 20070425; UY 30324 A 20070504; ZA 200809394 A 20081103