EP 2022789 A1 20090211 - Process for the preparation of a gastric acid secretion inhibitor
Title (en)
Process for the preparation of a gastric acid secretion inhibitor
Title (de)
Verfahren zur Herstellung eines Magensäuresekretionshemmers
Title (fr)
Procédé pour la préparation d'un inhibiteur de la sécrétion d'acide gastrique
Publication
Application
Priority
EP 07113888 A 20070806
Abstract (en)
The present process comprises the preparation of rabeprazole or a pharmaceutically acceptable salt thereof by oxidation in an acidic media of a N-oxide sulfide derivative compound, followed by a further selective reduction of the N-oxide obtained to afford rabeprazole.
IPC 8 full level
C07D 401/12 (2006.01)
CPC (source: EP)
C07D 401/12 (2013.01)
Citation (search report)
- [Y] WO 9840378 A1 19980917 - BRISTOL MYERS SQUIBB CO [US], et al
- [Y] ES 2063705 A1 19950101 - S A L V A T LAB SA [ES]
- [Y] EP 0174717 A1 19860319 - FISONS PLC [GB]
- [DA] EP 1409478 A1 20040421 - JANSSEN PHARMACEUTICA NV [BE]
- [DXY] RADL STANISLAV ET AL: "Synthetic studies connected with the preparation of H+/K+-ATPase inhibitors rabeprazole and lansoprazole", JOURNAL OF HETEROCYCLIC CHEMISTRY, HETEROCORPORATION. PROVO, US, vol. 43, no. 6, 2006, pages 1447 - 1453, XP002447852, ISSN: 0022-152X
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
DOCDB simple family (application)
EP 07113888 A 20070806