Global Patent Index - EP 2022789 A1

EP 2022789 A1 2009-02-11 - Process for the preparation of a gastric acid secretion inhibitor

Title (en)

Process for the preparation of a gastric acid secretion inhibitor

Title (de)

Verfahren zur Herstellung eines Magensäuresekretionshemmers

Title (fr)

Procédé pour la préparation d'un inhibiteur de la sécrétion d'acide gastrique

Publication

EP 2022789 A1 (EN)

Application

EP 07113888 A

Priority

EP 07113888 A

Abstract (en)

The present process comprises the preparation of rabeprazole or a pharmaceutically acceptable salt thereof by oxidation in an acidic media of a N-oxide sulfide derivative compound, followed by a further selective reduction of the N-oxide obtained to afford rabeprazole.

IPC 8 full level (invention and additional information)

C07D 401/12 (2006.01)

CPC (invention and additional information)

C07D 401/12 (2013.01)

Citation (search report)

  • [Y] WO 9840378 A1 19980917 - SQUIBB BRISTOL MYERS CO [US], et al
  • [Y] ES 2063705 A1 19950101 - S A L V A T LAB SA [ES]
  • [Y] EP 0174717 A1 19860319 - FISONS PLC [GB]
  • [DA] EP 1409478 A1 20040421 - JANSSEN PHARMACEUTICA NV [BE]
  • [DXY] RADL STANISLAV ET AL: "Synthetic studies connected with the preparation of H+/K+-ATPase inhibitors rabeprazole and lansoprazole", JOURNAL OF HETEROCYCLIC CHEMISTRY, HETEROCORPORATION. PROVO, US, vol. 43, no. 6, 2006, pages 1447 - 1453, XP002447852, ISSN: 0022-152X

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

EPO simple patent family

EP 2022789 A1 20090211

INPADOC legal status


2010-03-03 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20090812

2009-11-26 [REG DE 8566] DESIGNATED COUNTRY DE NOT LONGER VALID

2009-10-14 [AKX] PAYMENT OF DESIGNATION FEES

2009-02-11 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

2009-02-11 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Countries: AL BA HR MK RS