EP 2022852 A1 20090211 - METHOD FOR PRODUCTION OF OPTICALLY ACTIVE AMINE COMPOUND, RECOMBINANT VECTOR, AND TRANSFORMANT CARRYING THE VECTOR
Title (en)
METHOD FOR PRODUCTION OF OPTICALLY ACTIVE AMINE COMPOUND, RECOMBINANT VECTOR, AND TRANSFORMANT CARRYING THE VECTOR
Title (de)
VERFAHREN ZUR HERSTELLUNG EINER OPTISCH AKTIVEN AMINVERBINDUNG, REKOMBINANTER VEKTOR UND DEN VEKTOR TRAGENDE TRANSFORMANTE
Title (fr)
MÉTHODE DE PRODUCTION D'UN COMPOSÉ AMINE OPTIQUEMENT ACTIF, D'UN VECTEUR RECOMBINANT ET D'UN TRANSFORMANT PORTANT LEDIT VECTEUR
Publication
Application
Priority
- JP 2007060806 W 20070528
- JP 2006148623 A 20060529
Abstract (en)
The present invention relates to a method for producing an optically-active amine compound. The method is characterized by using a transaminase (A), an ±-keto acid reductase (B), and an enzyme (C), each having specific properties, in an identical reaction system to convert a ketone compound into a corresponding optically-active amine compound in which a carbon atom with an amino group bonded thereto serves as an asymmetric point. The present invention also relates to a recombinant vector for use in the method. The present invention makes it possible to efficiently produce an optically-active amine compound.
IPC 8 full level
C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12P 13/00 (2006.01); C12P 17/10 (2006.01)
CPC (source: EP US)
C12N 9/0004 (2013.01 - EP US); C12N 9/0006 (2013.01 - EP US); C12N 9/1096 (2013.01 - EP US); C12P 13/001 (2013.01 - EP US); C12P 13/002 (2013.01 - EP US); C12P 13/008 (2013.01 - EP US); C12P 17/10 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
EP 2022852 A1 20090211; EP 2022852 A4 20091104; EP 2022852 B1 20170705; EP 2022852 B8 20170823; JP 5410089 B2 20140205; JP WO2007139055 A1 20091008; US 2009148899 A1 20090611; US 8168412 B2 20120501; WO 2007139055 A1 20071206
DOCDB simple family (application)
EP 07744240 A 20070528; JP 2007060806 W 20070528; JP 2008517922 A 20070528; US 30246007 A 20070528