Global Patent Index - EP 2023912 A2

EP 2023912 A2 2009-02-18 - METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS IN COMBINATION THERAPY

Title (en)

METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS IN COMBINATION THERAPY

Title (de)

VERFAHREN UND ZUSAMMENSETZUNGEN UNTER VERWENDUNG IMMUNMODULATORISCHER VERBINDUNGEN IN DER KOMBINATIONSTHERAPIE

Title (fr)

MÉTHODES ET COMPOSITIONS FAISANT APPEL À DES COMPOSÉS IMMUNOMODULATEURS UTILISÉS EN TRAITEMENT COMBINÉ

Publication

EP 2023912 A2 (EN)

Application

EP 07795353 A

Priority

  • US 2007012495 W
  • US 80860206 P

Abstract (en)

[origin: WO2007139939A2] Provided herein are compositions comprising one or more immunomodulatory compounds and valproic acid, hydroxyurea or trichostatin A, methods for their use in CD34+ hematopoietic stem cell expansion in vitro and in vivo for bone marrow reconstitution and bone marrow transplantation, increasing fetal hemoglobin expression, and methods for treating, preventing and/or managing cancer, tumors and hematological diseases and disorders.

IPC 8 full level (invention and additional information)

A61K 31/165 (2006.01); A61K 31/17 (2006.01); A61K 31/19 (2006.01); A61K 31/454 (2006.01); A61P 7/06 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01)

CPC (invention and additional information)

A61K 31/454 (2013.01); A61K 31/165 (2013.01); A61K 31/17 (2013.01); A61K 31/19 (2013.01)

Citation (search report)

See references of WO 2007139939A3

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

EPO simple patent family

WO 2007139939 A2 20071206; WO 2007139939 A3 20080703; AU 2007267928 A1 20071206; CA 2652888 A1 20071206; CN 101495111 A 20090729; EP 2023912 A2 20090218; IL 195412 D0 20090803; JP 2009538318 A 20091105; KR 20090014393 A 20090210; MX 2008014912 A 20081210; RU 2008151713 A 20100710; RU 2426542 C2 20110820; ZA 200809956 B 20100728

INPADOC legal status


2013-04-03 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20121009

2010-10-27 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20100924

2009-04-01 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: VERHELLE, DOMINIQUE

2009-04-01 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: CHAN, KYLE

2009-04-01 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: CORRAL, LAURA

2009-04-01 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: MOUTOUH DE PARSEVAL, LAURE

2009-04-01 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: BRADY, HELEN

2009-02-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20081204

2009-02-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

2009-02-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Countries: AL BA HR MK RS