EP 2023912 A2 20090218 - METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS IN COMBINATION THERAPY
Title (en)
METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS IN COMBINATION THERAPY
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN UNTER VERWENDUNG IMMUNMODULATORISCHER VERBINDUNGEN IN DER KOMBINATIONSTHERAPIE
Title (fr)
MÉTHODES ET COMPOSITIONS FAISANT APPEL À DES COMPOSÉS IMMUNOMODULATEURS UTILISÉS EN TRAITEMENT COMBINÉ
Publication
Application
Priority
- US 2007012495 W 20070524
- US 80860206 P 20060526
Abstract (en)
[origin: WO2007139939A2] Provided herein are compositions comprising one or more immunomodulatory compounds and valproic acid, hydroxyurea or trichostatin A, methods for their use in CD34+ hematopoietic stem cell expansion in vitro and in vivo for bone marrow reconstitution and bone marrow transplantation, increasing fetal hemoglobin expression, and methods for treating, preventing and/or managing cancer, tumors and hematological diseases and disorders.
IPC 8 full level
A61K 31/165 (2006.01); A61K 31/17 (2006.01); A61K 31/19 (2006.01); A61K 31/454 (2006.01); A61P 7/06 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C12N 5/07 (2010.01); C12N 5/0789 (2010.01); C12N 5/095 (2010.01)
CPC (source: EP KR)
A61K 31/165 (2013.01 - EP); A61K 31/17 (2013.01 - EP KR); A61K 31/19 (2013.01 - EP KR); A61K 31/454 (2013.01 - EP KR); A61P 7/06 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 2007139939A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007139939 A2 20071206; WO 2007139939 A3 20080703; AU 2007267928 A1 20071206; CA 2652888 A1 20071206; CN 101495111 A 20090729; EP 2023912 A2 20090218; IL 195412 A0 20090803; JP 2009538318 A 20091105; KR 20090014393 A 20090210; MX 2008014912 A 20081210; RU 2008151713 A 20100710; RU 2426542 C2 20110820; ZA 200809956 B 20100728
DOCDB simple family (application)
US 2007012495 W 20070524; AU 2007267928 A 20070524; CA 2652888 A 20070524; CN 200780027722 A 20070524; EP 07795353 A 20070524; IL 19541208 A 20081120; JP 2009512164 A 20070524; KR 20087031357 A 20081224; MX 2008014912 A 20070524; RU 2008151713 A 20070524; ZA 200809956 A 20070524