EP 2024324 A1 20090218 - PROCESS FOR PREPARING GABAPENTIN
Title (en)
PROCESS FOR PREPARING GABAPENTIN
Title (de)
VERFAHREN ZUR HERSTELLUNG VON GABAPENTIN
Title (fr)
PROCEDE DE PREPARATION DE LA GABAPENTINE
Publication
Application
Priority
IE 2006000049 W 20060505
Abstract (en)
[origin: WO2007129286A1] A one pot process for preparing l-(aminomethyl)-cyclohexaneacetic acid or pharmaceutically acceptable salts thereof comprises the steps of hydrolysing 1-cyanocyclohexaneacetic acid ethyl ester with a potassium, sodium or lithium hydroxide to form a salt of 1-cyanocyclohexaneacetic acid; in-situ hydrogenating the salt of 1-cyanocyclohexaneacetic acid in the presence of a catalyst to form the salt of l-(aminomethyl)-cyclohexaneacetic acid; and isolating l-(aminomethyl)-cyclohexaneacetic acid.
IPC 8 full level
C07C 227/06 (2006.01); C07C 227/18 (2006.01); C07C 229/28 (2006.01)
CPC (source: EP)
C07C 227/04 (2013.01); C07C 229/28 (2013.01); C07C 253/30 (2013.01)
Citation (search report)
See references of WO 2007129286A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2007129286 A1 20071115; AU 2006343156 A1 20071115; BR PI0621665 A2 20111220; CA 2650978 A1 20071115; CN 101437787 A 20090520; EP 2024324 A1 20090218; IL 194977 A0 20090922
DOCDB simple family (application)
IE 2006000049 W 20060505; AU 2006343156 A 20060505; BR PI0621665 A 20060505; CA 2650978 A 20060505; CN 200680054486 A 20060505; EP 06728155 A 20060505; IL 19497708 A 20081029