Global Patent Index - EP 2024324 A1

EP 2024324 A1 2009-02-18 - PROCESS FOR PREPARING GABAPENTIN

Title (en)

PROCESS FOR PREPARING GABAPENTIN

Title (de)

VERFAHREN ZUR HERSTELLUNG VON GABAPENTIN

Title (fr)

PROCEDE DE PREPARATION DE LA GABAPENTINE

Publication

EP 2024324 A1 (EN)

Application

EP 06728155 A

Priority

IE 2006000049 W

Abstract (en)

[origin: WO2007129286A1] A one pot process for preparing l-(aminomethyl)-cyclohexaneacetic acid or pharmaceutically acceptable salts thereof comprises the steps of hydrolysing 1-cyanocyclohexaneacetic acid ethyl ester with a potassium, sodium or lithium hydroxide to form a salt of 1-cyanocyclohexaneacetic acid; in-situ hydrogenating the salt of 1-cyanocyclohexaneacetic acid in the presence of a catalyst to form the salt of l-(aminomethyl)-cyclohexaneacetic acid; and isolating l-(aminomethyl)-cyclohexaneacetic acid.

IPC 8 full level (invention and additional information)

C07C 227/18 (2006.01); C07C 227/06 (2006.01); C07C 229/28 (2006.01)

CPC (invention and additional information)

C07C 253/30 (2013.01); C07C 227/04 (2013.01); C07C 229/28 (2013.01)

Combination set (CPC)

C07C 253/30 + C07C 255/46

Citation (search report)

See references of WO 2007129286A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK YU

EPO simple patent family

WO 2007129286 A1 20071115; AU 2006343156 A1 20071115; BR PI0621665 A2 20111220; CA 2650978 A1 20071115; CN 101437787 A 20090520; EP 2024324 A1 20090218; IL 194977 D0 20090922

INPADOC legal status


2010-06-02 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20091201

2009-08-26 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) (DELETED)

2009-02-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20081205

2009-02-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

2009-02-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Countries: AL BA HR MK YU