Global Patent Index - EP 2024391 A2

EP 2024391 A2 2009-02-18 - CRYSTAL STRUCTURE OF CRIG AND C3B: CRIG COMPLEX

Title (en)

CRYSTAL STRUCTURE OF CRIG AND C3B: CRIG COMPLEX

Title (de)

KRISTALLSTRUKTUR FÜR CRIG UND C3B: CRIG-KOMPLEX

Title (fr)

STRUCTURE CRISTALLINE DE CRIg ET D'UN COMPLEXE C3b:CRIg

Publication

EP 2024391 A2 (EN)

Application

EP 07852376 A

Priority

  • US 2007012816 W
  • US 81027106 P
  • US 80622506 P
  • US 83936306 P

Abstract (en)

[origin: WO2008036135A2] The present invention concerns determination of the crystal structure of the macrophage specific receptor, CRIg (earlier referred to as STIgMA), and its complex with the C3b and C3c subunits of complement C3 (C3b:CRIg and C3c:CRIg complexes). The invention further concerns the use of the crystal structure of CRIg or the C3b:CRIg complex to screen for and identify molecules structurally and/or functionally related to CRIg, including CRIg agonists and antagonists.

IPC 8 full level (invention and additional information)

C07K 14/705 (2006.01); C30B 7/00 (2006.01); G01N 23/20 (2006.01); G06F 19/00 (2006.01)

CPC (invention and additional information)

C07K 14/70503 (2013.01); C30B 7/00 (2013.01); G01N 33/6863 (2013.01); C07K 2299/00 (2013.01); C07K 2319/30 (2013.01)

Citation (search report)

See references of WO 2008036135A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

EPO simple patent family

WO 2008036135 A2 20080327; WO 2008036135 A3 20081002; AU 2007297869 A1 20080327; AU 2007297869 A8 20090108; CA 2654438 A1 20080327; EP 2024391 A2 20090218; JP 2010505743 A 20100225

INPADOC legal status


2015-12-24 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1127362

2013-05-08 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20121019

2010-07-14 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20100610

2009-09-25 [REG HK DE] REQUESTS TO DESIGNATE PATENT IN HONG KONG

- Document: HK 1127362

2009-02-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20081218

2009-02-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

2009-02-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Countries: AL BA HR MK RS