EP 2026657 A1 20090225 - ANTI-CANCER COMPOSITION AND METHOD FOR USING THE SAME
Title (en)
ANTI-CANCER COMPOSITION AND METHOD FOR USING THE SAME
Title (de)
MITTEL GEGEN KREBS UND VERFAHREN ZU SEINER VERWENDUNG
Title (fr)
COMPOSITION ANTICANCÉREUSE ET SA MÉTHODE D'UTILISATION
Publication
Application
Priority
- US 2007069695 W 20070524
- US 80808106 P 20060524
- US 80998406 P 20060601
- US 87985707 P 20070111
Abstract (en)
[origin: WO2007140280A1] This invention encompasses an expeditious method and compositions that have been found to show selective cytotoxicity against several different cancer cell lines. for treating a wide variety cancer neoplasms that have tumor microenvironments by administering a stand-alone anti-tumor chemotherapeutic composition or administered as an adjunct with chemotherapy and/or radiotherapy with enhanced tumor site affinity that preferentially elevates the pH at the tumor site to suppress and eliminates the acidic tumor microenvironment, administered as chemosensitizing and/or radiosensitizers enhancing the tumor, suppression, remission and inhibit tumor metastisis. The invention encompasses controlling mechanisms of intracellular and extracellular ionic physiology through the administration of alkali salts for pH modulating and for restoring and enhancing ionic physiology. The compositions are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs), thereby inhibiting angiogenesis, reducing metastatic proliferation, supressing tumor generated induced acidotic pain.
IPC 8 full level
A61K 33/00 (2006.01); A61K 33/24 (2019.01); A61K 45/06 (2006.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); A61K 33/243 (2019.01)
CPC (source: EP US)
A61K 9/0014 (2013.01 - EP); A61K 33/00 (2013.01 - EP); A61K 33/24 (2013.01 - EP US); A61K 45/06 (2013.01 - EP); A61P 17/00 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61K 33/243 (2018.12 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007140280 A1 20071206; EP 2026657 A1 20090225; EP 2026657 A4 20091209
DOCDB simple family (application)
US 2007069695 W 20070524; EP 07784125 A 20070524