EP 2026789 A2 20090225 - NOVEL FORMULATION, ORIENTED TO TUMOUR PHYSIOLOGY, OF A CYTOSTATIC, IN PARTICULAR OF CIS-PLATINUM
Title (en)
NOVEL FORMULATION, ORIENTED TO TUMOUR PHYSIOLOGY, OF A CYTOSTATIC, IN PARTICULAR OF CIS-PLATINUM
Title (de)
NEUE, AN DER TUMORPHYSIOLOGIE ORIENTIERTE FORMULIERUNG EINES ZYTOSTATIKUMS, INSBESONDERE VON CIS-PLATIN
Title (fr)
NOUVELLE FORMULATION D'UN CYTOSTATIQUE, EN PARTICULIER LE CIS-PLATINE, ORIENTÉE EN FONCTION DE LA PHYSIOLOGIE TUMORALE
Publication
Application
Priority
- DE 2007000940 W 20070523
- DE 102006024528 A 20060523
Abstract (en)
[origin: WO2007134595A2] The invention relates to a pharmaceutical composition comprising: a) 0.01 to 4% by weight of a conjugate of a low molecular weight cytostatic with two or more reactive groups with a human-compatible protein, where the weight ratio of protein to cytostatic in the conjugate is 20:1 or higher, b) 0 to 0.9% by weight of NaCl, c) 0 to 5% by weight of a stabilization additive, d) 0 to 5% by weight of galenic additives and/or auxiliaries which are different from components b) and c), e) 0 to 5% by weight of a pharmacologically and/or diagnostically effective substance different from component a), or a mixture of various such substances, f) 19.9 to 99.9% by weight of water, where components a) to e) always add up to 100%. The invention further relates to uses of such compositions and to processes for their preparation.
IPC 8 full level
A61K 31/17 (2006.01); A61K 31/196 (2006.01); A61K 31/198 (2006.01); A61K 31/282 (2006.01); A61K 47/48 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP)
A61K 31/17 (2013.01); A61K 31/196 (2013.01); A61K 31/198 (2013.01); A61K 31/282 (2013.01); A61K 47/643 (2017.07); A61P 35/00 (2017.12)
Citation (search report)
See references of WO 2007134595A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
DE 102006024528 A1 20071129; EP 2026789 A2 20090225; WO 2007134595 A2 20071129; WO 2007134595 A3 20081016
DOCDB simple family (application)
DE 102006024528 A 20060523; DE 2007000940 W 20070523; EP 07764344 A 20070523