EP 2029743 A1 20090304 - METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY
Title (en)
METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY
Title (de)
VERFAHREN ZUR DIAGNOSE UND BEHANDLUNG VON SCHWANGERSCHAFTSKOMPLIKATIONEN
Title (fr)
MÉTHODES POUR LE DIAGNOSTIC ET LE TRAITEMENT DE COMPLICATIONS ASSOCIÉES À UNE GROSSESSE
Publication
Application
Priority
- US 2007012787 W 20070531
- US 44392006 A 20060531
- US 85276106 P 20061019
Abstract (en)
[origin: WO2008030283A1] Disclosed herein are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using combinations of compounds that alter soluble endoglin, endothelial nitric oxide synthase, PGI<SUB>2</SUB>, TGF-ßl, TGF-ß3, activin A, BMP2, BMP7, and sFlt-1 expression levels or biological activity. Also disclosed are methods of diagnosing a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, that include the measurement of any one or more of the following: soluble endoglin, endothelial nitric oxide synthase, PGI<SUB>2</SUB>, TGF-ßl, TGF-ß3, activin A, BMP2, BMP7, and sFlt-1 expression levels or biological activity.
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/70 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP KR)
A61K 31/4439 (2013.01 - EP); A61K 31/455 (2013.01 - EP); A61K 31/513 (2013.01 - EP); A61K 31/522 (2013.01 - EP); A61K 38/18 (2013.01 - KR); A61K 38/1841 (2013.01 - EP); A61K 38/1866 (2013.01 - EP); A61K 38/1875 (2013.01 - EP); A61K 38/486 (2013.01 - EP); A61K 38/4886 (2013.01 - EP); A61K 39/395 (2013.01 - KR); A61P 1/16 (2017.12 - EP); A61P 7/00 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 15/00 (2017.12 - EP); G01N 33/53 (2013.01 - KR); G01N 2800/368 (2013.01 - EP)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2008030283 A1 20080313; AU 2007293475 A1 20080313; BR PI0713122 A2 20120417; CA 2654283 A1 20080313; CN 101517078 A 20090826; EP 2029743 A1 20090304; EP 2029743 A4 20101208; JP 2009538915 A 20091112; KR 20090040874 A 20090427; MX 2008015197 A 20090623
DOCDB simple family (application)
US 2007012787 W 20070531; AU 2007293475 A 20070531; BR PI0713122 A 20070531; CA 2654283 A 20070531; CN 200780026858 A 20070531; EP 07795515 A 20070531; JP 2009513263 A 20070531; KR 20087032270 A 20081231; MX 2008015197 A 20070531