Global Patent Index - EP 2029743 A4

EP 2029743 A4 20101208 - METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY

Title (en)

METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY

Title (de)

VERFAHREN ZUR DIAGNOSE UND BEHANDLUNG VON SCHWANGERSCHAFTSKOMPLIKATIONEN

Title (fr)

MÉTHODES POUR LE DIAGNOSTIC ET LE TRAITEMENT DE COMPLICATIONS ASSOCIÉES À UNE GROSSESSE

Publication

EP 2029743 A4 20101208 (EN)

Application

EP 07795515 A 20070531

Priority

  • US 2007012787 W 20070531
  • US 44392006 A 20060531
  • US 85276106 P 20061019

Abstract (en)

[origin: WO2008030283A1] Disclosed herein are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using combinations of compounds that alter soluble endoglin, endothelial nitric oxide synthase, PGI<SUB>2</SUB>, TGF-ßl, TGF-ß3, activin A, BMP2, BMP7, and sFlt-1 expression levels or biological activity. Also disclosed are methods of diagnosing a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, that include the measurement of any one or more of the following: soluble endoglin, endothelial nitric oxide synthase, PGI<SUB>2</SUB>, TGF-ßl, TGF-ß3, activin A, BMP2, BMP7, and sFlt-1 expression levels or biological activity.

IPC 8 full level

C12N 15/09 (2006.01); A61K 31/70 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP KR)

A61K 31/4439 (2013.01 - EP); A61K 31/455 (2013.01 - EP); A61K 31/513 (2013.01 - EP); A61K 31/522 (2013.01 - EP); A61K 38/18 (2013.01 - KR); A61K 38/1841 (2013.01 - EP); A61K 38/1866 (2013.01 - EP); A61K 38/1875 (2013.01 - EP); A61K 38/486 (2013.01 - EP); A61K 38/4886 (2013.01 - EP); A61K 39/395 (2013.01 - KR); A61P 1/16 (2017.12 - EP); A61P 7/00 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 15/00 (2017.12 - EP); G01N 33/53 (2013.01 - KR); G01N 2800/368 (2013.01 - EP)

Citation (search report)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2008030283 A1 20080313; AU 2007293475 A1 20080313; BR PI0713122 A2 20120417; CA 2654283 A1 20080313; CN 101517078 A 20090826; EP 2029743 A1 20090304; EP 2029743 A4 20101208; JP 2009538915 A 20091112; KR 20090040874 A 20090427; MX 2008015197 A 20090623

DOCDB simple family (application)

US 2007012787 W 20070531; AU 2007293475 A 20070531; BR PI0713122 A 20070531; CA 2654283 A 20070531; CN 200780026858 A 20070531; EP 07795515 A 20070531; JP 2009513263 A 20070531; KR 20087032270 A 20081231; MX 2008015197 A 20070531