Global Patent Index - EP 2035837 B1

EP 2035837 B1 20120905 - PROTOCOL FOR MONITORING DIRECT THROMBIN INHIBITION

Title (en)

PROTOCOL FOR MONITORING DIRECT THROMBIN INHIBITION

Title (de)

VORSCHRIFT ZUR ÜBERWACHUNG VON DIREKTER THROMBINHEMMUNG

Title (fr)

PROTOCOLE DE SURVEILLANCE DE L'INHIBITION DIRECTE DE THROMBINE

Publication

EP 2035837 B1 20120905 (EN)

Application

EP 07762319 A 20070524

Priority

  • US 2007069655 W 20070524
  • US 80318406 P 20060525

Abstract (en)

[origin: WO2007140250A1] A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis parameters. The measured blood hemostasis parameters permit evaluation of hemostasis therapies including anticoagulation therapies such as direct thrombin inhibition therapies.

IPC 8 full level

G01N 33/86 (2006.01)

CPC (source: EP)

G01N 33/86 (2013.01); G01N 2333/974 (2013.01); G01N 2800/52 (2013.01)

Citation (examination)

  • NIELSEN V G ET AL: "Argatroban, Bivalirudin, and Lepirudin do not Decrease Clot Propagation and Strength as Effectively as Heparin-activated Antithrombin In Vitro", JOURNAL OF HEART AND LUNG TRANSPLANTATION, MOSBY-YEAR BOOK, INC., ST LOUIS, MO, US, vol. 25, no. 6, 1 June 2006 (2006-06-01), pages 653 - 663, XP025015228, ISSN: 1053-2498, [retrieved on 20060601]
  • KOSTER A ET AL: "Monitoring of bivalirudin anticoagulation during and after cardiopulmonary bypass using an ecarin-activated TEG(R) system", JOURNAL OF CARDIAC SURGERY 200807 US LNKD- DOI:10.1111/J.1540-8191.2008.00604.X, vol. 23, no. 4, July 2008 (2008-07-01), pages 321 - 323, ISSN: 0886-0440

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2007140250 A1 20071206; EP 2035837 A1 20090318; EP 2035837 B1 20120905

DOCDB simple family (application)

US 2007069655 W 20070524; EP 07762319 A 20070524