Global Patent Index - EP 2036893 A1

EP 2036893 A1 20090318 - Abl KINASE INHIBITOR

Title (en)

Abl KINASE INHIBITOR

Title (de)

ABL-KINASE-INHIBITOR

Title (fr)

INHIBITEUR DE KINASE Abl

Publication

EP 2036893 A1 20090318 (EN)

Application

EP 07767882 A 20070629

Priority

  • JP 2007063095 W 20070629
  • JP 2006180530 A 20060630

Abstract (en)

The present invention provides an Abelson kinase (Abl kinase) inhibitor which comprises, as an active ingredient, an indazole derivative represented by Formula (I) (wherein R 1 represents substituted or unsubstituted aryl or a substituted or unsubstituted heterocyclic group) or a pharmaceutically acceptable salt thereof, an Abl kinase inhibitor which comprises, as an active ingredient, an indazole derivative represented by Formula (Ia) [wherein R 2 represents CONR 4a R 4b (wherein R 4a and R 4b may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like, or R 4a and R 4b are combined together with the adjacent nitrogen atom thereto to form a substituted or unsubstituted heterocyclic group) or the like, and R 3 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like] or a pharmaceutically acceptable salt thereof, and the like.

IPC 8 full level

C07D 231/56 (2006.01); A61K 31/416 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 43/00 (2006.01); C07D 401/06 (2006.01); C07D 403/10 (2006.01)

CPC (source: EP US)

A61K 31/416 (2013.01 - EP US); A61K 31/4439 (2013.01 - EP US); A61K 31/454 (2013.01 - EP US); A61K 31/496 (2013.01 - EP US); A61K 31/5377 (2013.01 - EP US); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 231/56 (2013.01 - EP US); C07D 401/06 (2013.01 - EP US); C07D 403/10 (2013.01 - EP US); C07D 413/12 (2013.01 - EP US)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

DOCDB simple family (publication)

EP 2036893 A1 20090318; EP 2036893 A4 20110413; CN 101484427 A 20090715; JP WO2008001885 A1 20091126; US 2012329794 A1 20121227; WO 2008001885 A1 20080103

DOCDB simple family (application)

EP 07767882 A 20070629; CN 200780024923 A 20070629; JP 2007063095 W 20070629; JP 2008522648 A 20070629; US 30514607 A 20070629