EP 2037935 A1 20090325 - PHARMACEUTICAL PREPARATIONS FOR CONTRACEPTION AND FOR PREVENTING THE RISK OF CONGENITAL MALFORMATIONS
Title (en)
PHARMACEUTICAL PREPARATIONS FOR CONTRACEPTION AND FOR PREVENTING THE RISK OF CONGENITAL MALFORMATIONS
Title (de)
PHARMAZEUTISCHE ZUBEREITUNG ZUR KONTRAZEPTION UND ZUR VERMINDERUNG DES RISIKOS ANGEBORENER FEHLBILDUNGEN
Title (fr)
PRÉPARATION PHARMACEUTIQUE DESTINÉE À LA CONTRACEPTION ET À ÉVITER LES RISQUES DE MALFORMATIONS CONGÉNITALES
Publication
Application
Priority
- EP 2007003982 W 20070505
- EP 06014002 A 20060706
- EP 06016950 A 20060814
- EP 07724906 A 20070505
Abstract (en)
[origin: WO2008003363A1] The invention relates to a pharmaceutical composition for contraception containing, in a daily dose, 2.0 mg or 1.5 mg of 17a-cyanomethyl-17-ß-hydroxyestra-4,9-diene-3on (dienogest) and 0.015 mg of 17a-ethinylestradiol (ethinylestradiol) and (6S)-5-methyltetrahydrofolate, preferably as calcium salt of the (6S)-5-methyltetrahydrofolic acid (metafolin) together with one or more pharmaceutically acceptable auxiliary agents/carriers. The inventive pharmaceutical composition is an oral contraceptive as well as an agent for reducing the risk of congenital malformations. The invention also relates to a kit comprising 21 daily dose units of the pharmaceutical composition and 7 daily dose units containing only (6S)-5-methyltetrahydrofolate, preferably also metafolin.
IPC 8 full level
A61K 31/57 (2006.01); A61K 31/519 (2006.01); A61P 15/00 (2006.01)
CPC (source: EP KR US)
A61K 31/519 (2013.01 - EP KR US); A61K 31/565 (2013.01 - KR); A61K 31/567 (2013.01 - EP US); A61P 15/00 (2017.12 - EP); A61P 15/18 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 2008003363A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2008003363 A1 20080110; AR 061959 A1 20080810; BR PI0713999 A2 20121120; CA 2665788 A1 20080110; CL 2007001961 A1 20080111; DE 112007001600 A5 20090430; EP 2037935 A1 20090325; IL 196154 A0 20090922; JP 2009542588 A 20091203; KR 20090029824 A 20090323; MX 2009000256 A 20090218; PE 20080400 A1 20080704; RU 2009102443 A 20100820; TW 200810764 A 20080301; US 2008268048 A1 20081030; UY 30461 A1 20080229
DOCDB simple family (application)
EP 2007003982 W 20070505; AR P070103017 A 20070706; BR PI0713999 A 20070505; CA 2665788 A 20070505; CL 2007001961 A 20070705; DE 112007001600 T 20070505; EP 07724906 A 20070505; IL 19615408 A 20081224; JP 2009516918 A 20070505; KR 20097002387 A 20090205; MX 2009000256 A 20070505; PE 2007000865 A 20070705; RU 2009102443 A 20070505; TW 96124769 A 20070706; US 77303707 A 20070703; UY 30461 A 20070704