EP 2041134 A1 20090401 - NOVEL 1,4-DIAZA-BICYCLOÝ3.2.2¨NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE
Title (en)
NOVEL 1,4-DIAZA-BICYCLOÝ3.2.2¨NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE
Title (de)
NEUE 1,4-DIAZABICYCLO[3.2.2]NONYLPYRIMIDINYLDERIVATE UND IHRE MEDIZINISCHE VERWENDUNG
Title (fr)
NOUVEAUX DÉRIVÉS DE 1,4-DIAZA-BICYCLOÝ3.2.2¨NONYL PYRIMIDINYLE ET LEUR UTILISATION MÉDICALE
Publication
Application
Priority
- EP 2007055170 W 20070529
- DK PA200600730 A 20060530
- US 80902306 P 20060530
Abstract (en)
[origin: WO2007138039A1] This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
IPC 8 full level
C07D 471/08 (2006.01); A61K 31/551 (2006.01); A61P 25/00 (2006.01)
CPC (source: EP US)
A61P 1/00 (2017.12 - EP); A61P 1/04 (2017.12 - EP); A61P 1/12 (2017.12 - EP); A61P 1/14 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/06 (2017.12 - EP); A61P 9/08 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 15/06 (2017.12 - EP); A61P 15/08 (2017.12 - EP); A61P 15/10 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 17/10 (2017.12 - EP); A61P 17/14 (2017.12 - EP); A61P 21/00 (2017.12 - EP); A61P 21/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/02 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/10 (2017.12 - EP); A61P 25/12 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/20 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 25/30 (2017.12 - EP); A61P 25/32 (2017.12 - EP); A61P 25/34 (2017.12 - EP); A61P 25/36 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 471/08 (2013.01 - EP US)
Citation (search report)
See references of WO 2007138039A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007138039 A1 20071206; AU 2007267176 A1 20071206; AU 2007267177 A1 20071206; AU 2007267178 A1 20071206; CA 2653371 A1 20071206; CA 2653460 A1 20071206; CA 2653681 A1 20071206; EP 2029595 A1 20090304; EP 2029595 B1 20110921; EP 2041134 A1 20090401; EP 2049538 A1 20090422; JP 2009538868 A 20091112; JP 2009538869 A 20091112; JP 2009538870 A 20091112; MX 2008014885 A 20081205; MX 2008014889 A 20081205; MX 2008014890 A 20081205; US 2009181984 A1 20090716; US 2009197872 A1 20090806; US 2009270403 A1 20091029; US 7915272 B2 20110329; US 8148365 B2 20120403; WO 2007138040 A1 20071206; WO 2007138040 A8 20081120; WO 2007138041 A1 20071206; WO 2007138041 A8 20081120
DOCDB simple family (application)
EP 2007055170 W 20070529; AU 2007267176 A 20070529; AU 2007267177 A 20070529; AU 2007267178 A 20070529; CA 2653371 A 20070529; CA 2653460 A 20070529; CA 2653681 A 20070529; EP 07729592 A 20070529; EP 07729593 A 20070529; EP 07729594 A 20070529; EP 2007055171 W 20070529; EP 2007055172 W 20070529; JP 2009512570 A 20070529; JP 2009512571 A 20070529; JP 2009512572 A 20070529; MX 2008014885 A 20070529; MX 2008014889 A 20070529; MX 2008014890 A 20070529; US 29910607 A 20070529; US 29910807 A 20070529; US 29911407 A 20070529