EP 2041316 A4 20091209 - A METHOD OF MODIFYING A MACROMOLECULE WITHOUT PRIOR EXTRACTION FROM A SAMPLE
Title (en)
A METHOD OF MODIFYING A MACROMOLECULE WITHOUT PRIOR EXTRACTION FROM A SAMPLE
Title (de)
VERFAHREN ZUR MODIFIZIERUNG EINES MAKROMOLEKÜLS OHNE VORHERGEHENDE EXTRAKTION AUS EINER PROBE
Title (fr)
PROCÉDÉ DE MODIFICATION D'UNE MACROMOLÉCULE SANS EXTRACTION PRÉALABLE D'UN ÉCHANTILLON
Publication
Application
Priority
- US 2007015329 W 20070629
- US 81787606 P 20060629
- US 82879006 P 20061010
Abstract (en)
[origin: WO2008002680A2] The present invention encompasses a method of modifying a macromolecule without prior extraction from a sample by converting the macromolecule in the sample with a chemical, removing or converting chemical intermediates, if necessary; and purifying the resulting modified macromolecule.
IPC 8 full level
C12Q 1/68 (2006.01); C12N 5/07 (2010.01); C12N 5/077 (2010.01); C12N 15/117 (2010.01)
CPC (source: EP KR)
C12N 15/1006 (2013.01 - EP KR); C12N 15/102 (2013.01 - EP KR); C12Q 1/6806 (2013.01 - KR); G01N 33/48 (2013.01 - KR)
Citation (search report)
- [XI] WO 2004067775 A2 20040812 - EPIGENOMICS AG [DE], et al
- [XI] OLEK A; ET AL: "A modified an improved method for bisulphite based cytosine methylation analysis", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 24, no. 24, 1 January 1996 (1996-01-01), pages 5064 - 5066, XP002106408, ISSN: 0305-1048
- [A] GRUNAU C; CLARK S J; ROSENTHAL A: "Bisulfite genomic sequencing: systematic investigation of critical experimental parameters", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 29, no. 13, 1 January 2001 (2001-01-01), pages E65 - 1, XP002241346, ISSN: 0305-1048
- [A] SHIRAISHI MASAHIKO; HAYATSU HIKOYA: "High-speed conversion of cytosine to uracil in bisulfite genomic sequencing analysis of DNA methylation.", DNA RESEARCH : AN INTERNATIONAL JOURNAL FOR RAPID PUBLICATION OF REPORTS ON GENES AND GENOMES 31 DEC 2004, vol. 11, no. 6, 31 December 2004 (2004-12-31), pages 409 - 415, XP002545192, ISSN: 1340-2838
- See references of WO 2008002680A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008002680 A2 20080103; WO 2008002680 A3 20081127; BR PI0713927 A2 20130108; CA 2656327 A1 20080103; EP 2041316 A2 20090401; EP 2041316 A4 20091209; IL 196198 A0 20090922; JP 2009542216 A 20091203; KR 20090036121 A 20090413; MX 2009000122 A 20090126
DOCDB simple family (application)
US 2007015329 W 20070629; BR PI0713927 A 20070629; CA 2656327 A 20070629; EP 07810136 A 20070629; IL 19619808 A 20081225; JP 2009518328 A 20070629; KR 20097001936 A 20090129; MX 2009000122 A 20070629