EP 2043643 A2 20090408 - USE OF DERIVATIVES OF IMIDAZO[1, 2-A]PYRIDINE-2-CARBOXAMIDES IN THERAPEUTICS
Title (en)
USE OF DERIVATIVES OF IMIDAZO[1, 2-A]PYRIDINE-2-CARBOXAMIDES IN THERAPEUTICS
Title (de)
VERWENDUNG VON IMIDAZO [1, 2-A]PYRIDIN-2-CARBOXAMIDEN FÜR THERAPEUTIKA
Title (fr)
UTILISATION DE DÉRIVÉS D'IMIDAZO[1, 2-A]PYRIDINE-2-CARBOXAMIDES EN THÉRAPEUTIQUE
Publication
Application
Priority
- FR 2007001127 W 20070703
- FR 0606013 A 20060703
Abstract (en)
[origin: WO2008003858A2] The invention relates to the use of compounds having formula (I), in which: R<SUB>1,</SUB> R<SUB>2,</SUB> R<SUB>3</SUB> and R<SUB>4</SUB> are hydrogen and X is a phenyl group that is optionally substituted by one or more groups selected independently from among the atoms and groups comprising halogen, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, cyclo(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, cyclo(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy and NRaRb; or R<SUB>2 </SUB>is chlorine and X is a para-fluoro-phenyl; or R<SUB>3</SUB> is a methyl and X is a non-substituted phenyl group; or R<SUB>1</SUB> is a methly and X is a non-substituted phenyl group; and Ra and Rb are, independently of each other, hydrogen, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl or together with the nitrogen atom form a 4-7-link ring, said compounds taking the form of a base or an acid addition salt. The invention is intended for the preparation of a medicament for the treatment and prevention of diseases involving the NOT receptor.
IPC 8 full level
A61K 31/437 (2006.01); A61K 31/454 (2006.01)
CPC (source: EP KR US)
A61K 31/437 (2013.01 - EP US); A61K 31/454 (2013.01 - EP KR US); A61P 19/00 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 25/08 (2018.01 - EP); A61P 25/14 (2018.01 - EP); A61P 25/16 (2018.01 - EP); A61P 25/18 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 25/30 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 487/04 (2013.01 - KR)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2903108 A1 20080104; FR 2903108 B1 20080829; AU 2007271010 A1 20080110; BR PI0714317 A2 20140624; CA 2656363 A1 20080110; CN 101484168 A 20090715; EP 2043643 A2 20090408; IL 195949 A0 20090901; JP 2009541473 A 20091126; KR 20090034861 A 20090408; MX 2008016550 A 20090212; RU 2009103302 A 20100810; US 2009149494 A1 20090611; WO 2008003858 A2 20080110; WO 2008003858 A3 20080417
DOCDB simple family (application)
FR 0606013 A 20060703; AU 2007271010 A 20070703; BR PI0714317 A 20070703; CA 2656363 A 20070703; CN 200780025224 A 20070703; EP 07803835 A 20070703; FR 2007001127 W 20070703; IL 19594908 A 20081215; JP 2009517334 A 20070703; KR 20097000051 A 20090102; MX 2008016550 A 20070703; RU 2009103302 A 20070703; US 33701808 A 20081217