Global Patent Index - EP 2045269 A1

EP 2045269 A1 20090408 - Novel chimeric analgesic peptides

Title (en)

Novel chimeric analgesic peptides

Title (de)

Neuartige chimärische analgetische Peptide

Title (fr)

Nouveaux peptides analgésiques chimériques

Publication

EP 2045269 A1 20090408 (EN)

Application

EP 08162559 A 20001027

Priority

  • EP 00973993 A 20001027
  • US 42869299 A 19991028

Abstract (en)

There is provided a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia.

IPC 8 full level

C07K 19/00 (2006.01); A61K 38/00 (2006.01); C07K 7/22 (2006.01)

CPC (source: EP US)

A61P 25/00 (2017.12 - EP); C07K 7/22 (2013.01 - EP US); C07K 19/00 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)

Citation (applicant)

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Citation (search report)

  • [X] ULO LANGEL ET AL: "DESIGN OF CHIMERIC PEPTIDE LIGANDS TO GALANIN RECEPTORS AND SUBSTANCE P RECEPTORS", INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH,DK,MUNKSGAARD, COPENHAGEN, vol. 39, no. 6, 1 June 1992 (1992-06-01), pages 516 - 522, XP000288101, ISSN: 0367-8377
  • [Y] KREAM RICHARD M ET AL: "Substance P markedly potentiates the antinociceptive effects of morphine sulfate administered at the spinal level.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 90, no. 8, 1993, 1993, pages 3564 - 3568, XP002167021, ISSN: 0027-8424
  • [Y] MASZCZYNSKA IWONA ET AL: "Alternative forms of interaction of substance P and opioids in nociceptive transmission.", LETTERS IN PEPTIDE SCIENCE, vol. 5, no. 5-6, October 1998 (1998-10-01), pages 395 - 398, XP000995737, ISSN: 0929-5666
  • [Y] MASZCZYNSKA IWONA ET AL: "Dual functional interactions of Substance P and Opioids in Nociceptive Transmission: Review and Reconciliation", ANALGESIA, vol. 3, 1998, pages 259 - 268, XP000995994
  • [Y] FORAN STACY E ET AL: "Chimeric peptide for the treatment of acute and chronic pain.", ANESTHESIOLOGY (HAGERSTOWN), vol. 91, no. 3A, 1999, Annual Meeting of the American Society of Anesthesiologists;Dallas, Texas, USA; October 9-13, 1999, pages A944, XP000996135, ISSN: 0003-3022
  • [PX] FORAN STACY E ET AL: "A substance P-opioid chimeric peptide as a unique nontolerance-forming analgesic.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 97, no. 13, 30 June 2000 (2000-06-30), June 30, 2000, pages 7621 - 7626, XP002167022, ISSN: 0027-8424
  • [T] ZUBRZYCKA M ET AL: "Interactions of Galanin with Endomorphin-2, Vasopressin and Oxytocin in Nociceptive Modulation of the Trigemino-Hypoglossal Reflex in Rats", PHYSIOLOGICAL RESEARCH, vol. 57, no. 5, 2008, pages 769 - 776, XP002513734, ISSN: 0862-8408

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0130371 A2 20010503; WO 0130371 A3 20011122; AT E405281 T1 20080915; AU 1243201 A 20010508; CA 2390084 A1 20010503; DE 60040008 D1 20081002; EP 1227829 A2 20020807; EP 1227829 B1 20080820; EP 2045269 A1 20090408; ES 2312369 T3 20090301; US 2006105947 A1 20060518; US 2009298755 A1 20091203; US 6759520 B1 20040706

DOCDB simple family (application)

US 0029789 W 20001027; AT 00973993 T 20001027; AU 1243201 A 20001027; CA 2390084 A 20001027; DE 60040008 T 20001027; EP 00973993 A 20001027; EP 08162559 A 20001027; ES 00973993 T 20001027; US 42869299 A 19991028; US 69287207 A 20070328; US 82862304 A 20040421