EP 2047857 A4 20100526 - AGENT FOR INJECTION PURPOSES COMPRISING ANTIBIOTIC, AND SOLUTION FOR INJECTION COMPRISING THE AGENT
Title (en)
AGENT FOR INJECTION PURPOSES COMPRISING ANTIBIOTIC, AND SOLUTION FOR INJECTION COMPRISING THE AGENT
Title (de)
MITTEL FÜR INJEKTIONSZWECKE MIT EINEM ANTIBIOTIKUM UND DAS MITTEL ENTHALTENDE LÖSUNG ZUR INJEKTION
Title (fr)
AGENT DESTINÉ À ÊTRE UTILISÉ POUR UNE INJECTION COMPRENANT UN ANTIBIOTIQUE ET SOLUTION POUR INJECTION COMPRENANT L'AGENT
Publication
Application
Priority
- JP 2007063003 W 20070628
- JP 2006179778 A 20060629
Abstract (en)
[origin: EP2047857A1] A pharmaceutical composition for injection comprising a depsipeptide antibiotic, WAP-8294A 2 , as an active ingredient, which is stable and contains WAP-8294A 2 in high concentrations is provided. This composition comprises WAP-8294A 2 of the following structural formula (1) as an active ingredient and is characterized in that 2-hydroxypropyl-²-cyclodextrin or ²-cyclodextrin is contained as a stabilizer or solubilizer and the pH of the composition is not adjusted. This composition is mixed with a pH-adjusting agent such as dextrose and with an infusion or diluent comprising a solution of disodium hydrogen phosphate, sodium dihydrogen phosphate, and sodium hydroxide at the time of use to prepare a solution for intravenous administration of WAP-8294A 2 .
IPC 8 full level
A61K 38/00 (2006.01); A61K 9/08 (2006.01); A61K 47/04 (2006.01); A61K 47/26 (2006.01); A61K 47/40 (2006.01); A61P 31/04 (2006.01)
CPC (source: EP KR US)
A61K 9/0019 (2013.01 - EP US); A61K 9/08 (2013.01 - KR); A61K 38/15 (2013.01 - EP KR US); A61K 47/40 (2013.01 - EP KR US); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP)
Citation (search report)
- [Y] US 5648455 A 19970715 - OHASHI YOSHITAMI [JP], et al
- [Y] US 2005239692 A1 20051027 - LINDENBLATT HILTRUD [DE], et al
- [Y] US 2003220237 A1 20031127 - OHNAKA CHIKA [JP], et al
- [A] WO 0062793 A2 20001026 - LILLY CO ELI [US], et al
- [A] US 2004072797 A1 20040415 - ARAMWIT PORNANONG [US], et al
- See references of WO 2008001849A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 2047857 A1 20090415; EP 2047857 A4 20100526; EP 2047857 B1 20120104; AT E539761 T1 20120115; AU 2007266063 A1 20080103; AU 2007266063 B2 20110908; BR PI0713080 A2 20121009; CA 2656604 A1 20080103; CA 2656604 C 20140107; CN 101578103 A 20091111; CN 101578103 B 20130925; DK 2047857 T3 20120227; ES 2378279 T3 20120410; JP 5272126 B2 20130828; JP WO2008001849 A1 20091126; KR 101286038 B1 20130719; KR 20090030317 A 20090324; MX 2009000155 A 20090325; PL 2047857 T3 20120531; PT 2047857 E 20120315; RU 2009102803 A 20100810; RU 2462261 C2 20120927; SI 2047857 T1 20120330; US 2009258920 A1 20091015; US 7968588 B2 20110628; WO 2008001849 A1 20080103
DOCDB simple family (application)
EP 07767796 A 20070628; AT 07767796 T 20070628; AU 2007266063 A 20070628; BR PI0713080 A 20070628; CA 2656604 A 20070628; CN 200780032266 A 20070628; DK 07767796 T 20070628; ES 07767796 T 20070628; JP 2007063003 W 20070628; JP 2008522624 A 20070628; KR 20097001274 A 20070628; MX 2009000155 A 20070628; PL 07767796 T 20070628; PT 07767796 T 20070628; RU 2009102803 A 20070628; SI 200730847 T 20070628; US 30666307 A 20070628