Global Patent Index - EP 2051699 A4

EP 2051699 A4 20130327 - PHOTOSENSITIZER FORMULATIONS FOR TOPICAL APPLICATIONS

Title (en)

PHOTOSENSITIZER FORMULATIONS FOR TOPICAL APPLICATIONS

Title (de)

PHOTOSENSIBILISATORFORMULIERUNGEN FÜR TOPISCHE ANWENDUNGEN

Title (fr)

PRÉPARATIONS DE PHOTOSENSIBILISATEURS POUR APPLICATION TOPIQUE

Publication

EP 2051699 A4 20130327 (EN)

Application

EP 07776843 A 20070508

Priority

  • US 2007011045 W 20070508
  • US 79937306 P 20060510
  • US 80014707 A 20070504

Abstract (en)

[origin: WO2007133514A2] Highly flexible penetrating liposomal carrier systems are formulated with enhanced skin penetration properties. These specialized formulations of highly flexible penetrating liposomal delivery systems comprise one or more phospholipids, lysophosphatides and hydrophobic photosensitizer. This new formulations can squeeze liposomal particles through intercellular regions of stratum corneum as intact structures, and, in this way, deliver encapsulated photosensitizer to the epidermis, dermis, hypodermis and surroundings. The penetrating liposomal formulation provides therapeutically effective amounts of the hydrophobic photosensitizer through topical application with better skin penetration thus improving drug targeting and the efficacy of photodynamic therapy (PDT).

IPC 8 full level

A61K 9/127 (2006.01); A61K 9/00 (2006.01); A61K 41/00 (2006.01)

CPC (source: EP)

A61K 9/0014 (2013.01); A61K 9/127 (2013.01); A61K 41/0071 (2013.01)

Citation (search report)

  • [XY] US 5616602 A 19970401 - TAYLOR PETER W [GB], et al
  • [Y] US 2005048109 A1 20050303 - ALBRECHT VOLKER [DE], et al
  • [Y] BLUME A ET AL: "Interaction of phospholipid liposomes with lipid model mixtures for stratum corneum lipids", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 99, no. 2-3, 15 October 1993 (1993-10-15), pages 219 - 228, XP025568572, ISSN: 0378-5173, [retrieved on 19931015], DOI: 10.1016/0378-5173(93)90364-L
  • [Y] BOIX A ET AL: "Estimation of Transdermal Permeation Parameters in Non-stationary Diffusion Experiments. Application to Pre-treatment Studies with Terpenes", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 22, no. 1, 1 January 2005 (2005-01-01), pages 94 - 102, XP019370696, ISSN: 1573-904X, DOI: 10.1007/S11095-004-9014-2

Designated contracting state (EPC)

DE ES FR GB IT

DOCDB simple family (publication)

WO 2007133514 A2 20071122; WO 2007133514 A3 20080424; EP 2051699 A2 20090429; EP 2051699 A4 20130327; EP 2051699 B1 20180926; US 2009081281 A1 20090326

DOCDB simple family (application)

US 2007011045 W 20070508; EP 07776843 A 20070508; US 22689307 A 20070508