Global Patent Index - EP 2053032 A4

EP 2053032 A4 20120404 - METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVE OR SALT THEREOF

Title (en)

METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVE OR SALT THEREOF

Title (de)

VERFAHREN ZUR HERSTELLUNG EINES OPTISCH AKTIVEN HYDROXYCARBONSÄUREDERIVATS ODER SALZES DAVON

Title (fr)

PROCÉDÉ DE PRÉPARATION DÉRIVÉ D'ACIDE HYDROXYCARBOXYLIQUE OPTIQUEMENT ACTIF OU DE SON SEL

Publication

EP 2053032 A4 20120404 (EN)

Application

EP 07805906 A 20070808

Priority

  • JP 2007065559 W 20070808
  • JP 2006216771 A 20060809

Abstract (en)

[origin: EP2053032A1] The present invention has its object to provide a method for producing an optically active hydroxycarboxylic acid derivative which is an intermediate important for production of medicines, agrochemicals, chemical products, and so on. The production method of the present invention comprises: carrying out a hydrogen-transfer reduction of a ketocarboxylic acid or a salt thereof by the reaction of an optically active diamine complex to produce an optically active hydroxycarboxylic acid derivative. According to the present invention, it is possible to safely and efficiently produce an industrially-useful optically active hydroxycarboxylic acid derivative.

IPC 8 full level

C07B 53/00 (2006.01); C07C 51/367 (2006.01); C07C 59/48 (2006.01); C07C 201/12 (2006.01); C07C 205/56 (2006.01)

CPC (source: EP US)

C07B 53/00 (2013.01 - EP US); C07C 51/00 (2013.01 - EP US); C07C 51/367 (2013.01 - EP US); C07C 201/12 (2013.01 - EP US); C07B 2200/07 (2013.01 - EP US)

C-Set (source: EP US)

  1. C07C 51/367 + C07C 59/48
  2. C07C 201/12 + C07C 205/56

Citation (search report)

  • [A] MATHARU, D.S. ET AL.: "An outstanding catalyst for asymmetric transfer hydrogenation in aqueous solution and formic acid/triethylamine", CHEMICAL COMMUNICATIONS, no. 30, 23 June 2006 (2006-06-23), pages 3232 - 3234, XP055019666, ISSN: 1359-7345, DOI: 10.1039/b606288a
  • [AD] WANG, Z. ET AL.: "Enantioselective Synthesis of alpha-Hydroxy Carboxylic Acids: Direct Conversion of alpha-Oxocarboxylic Acids to Enantiomerically Enriched alpha-Hydroxy Carboxylic Acids via Neighboring Group Control", TETRAHEDRON LETTERS, vol. 39, no. 31, 1998, pages 5501 - 5504, XP004124099, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(98)01162-9
  • [AD] SPINDLER, F. ET AL.: "A highly enantioselective rhodium catalyst for the hydrogenation of aliphatic alpha-keto esters", CHIRALITY, vol. 3, no. 4, 1991, pages 370 - 375, XP055019555, ISSN: 0899-0042, DOI: 10.1002/chir.530030423
  • See also references of WO 2008018520A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

EP 2053032 A1 20090429; EP 2053032 A4 20120404; JP WO2008018520 A1 20100107; US 2010191011 A1 20100729; US 8058471 B2 20111115; WO 2008018520 A1 20080214

DOCDB simple family (application)

EP 07805906 A 20070808; JP 2007065559 W 20070808; JP 2008528863 A 20070808; US 37680307 A 20070808