EP 2054515 A2 20090506 - USE OF A PHAGE DISPLAYING A PEPTIDE FROM AN ADHESION PROTEIN FOR TREATING A DISEASE ASSOCIATED WITH INTRACELLULAR FORMATION OF PROTEIN FIBRILLAR INCLUSIONS OR AGGREGATES
Title (en)
USE OF A PHAGE DISPLAYING A PEPTIDE FROM AN ADHESION PROTEIN FOR TREATING A DISEASE ASSOCIATED WITH INTRACELLULAR FORMATION OF PROTEIN FIBRILLAR INCLUSIONS OR AGGREGATES
Title (de)
VERWENDUNG EINES PHAGEN MIT ANZEIGE EINES PEPTIDS EINES ADHÄSIONSPROTEINS ZUR BEHANDLUNG EINER ERKRANKUNG IM ZUSAMMENHANG MIT INTRAZELLULÄRER BILDUNG VON FIBRILLÄREN PROTEINEINSCHLÜSSEN ODER AGGREGRATEN
Title (fr)
PROCÉDÉ D'INHIBITION OU DE TRAITEMENT D'UNE MALADIE ASSOCIÉE À LA FORMATION INTRACELLULAIRE D'INCLUSIONS OU D'AGRÉGATS FIBRILLAIRES PROTÉIQUES
Publication
Application
Priority
- US 2007073858 W 20070719
- US 83222906 P 20060721
Abstract (en)
[origin: WO2008011503A2] A therapeutic agent which carries a peptide sequence containing a mammalian cell adhesion sequence can be used to inhibit or treat diseases associated with intracellular formation of protein fibrillar inclusions or aggregates, to inhibit the intracellular formation of protein fibrillar inclusions or aggregates, and to disaggregate pre-formed intracellular protein fibrillar inclusions or aggregates. Filamentous bacteriophage which displays a non-filamentous bacteriophage RGD cell adhesion sequence on its surface, but not an antibody or non-filamentous bacteriophage antigen other than said RGD cell adhesion sequence, is a preferred embodiment of such a therapeutic agent.
IPC 8 full level
C12N 15/10 (2006.01); A61K 35/76 (2006.01); A61K 48/00 (2006.01); A61P 25/28 (2006.01); C12N 7/04 (2006.01)
CPC (source: EP US)
A61P 21/04 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 14/005 (2013.01 - EP US); C12N 7/00 (2013.01 - EP US); A61K 35/00 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); C07K 2319/01 (2013.01 - EP US); C12N 2795/14122 (2013.01 - EP US); C12N 2795/14161 (2013.01 - EP US); C12N 2810/405 (2013.01 - EP US)
Citation (search report)
See references of WO 2008011503A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2008011503 A2 20080124; WO 2008011503 A3 20080626; AT E541038 T1 20120115; AU 2007275258 A1 20080124; CA 2659032 A1 20080124; CN 101553567 A 20091007; EP 2054515 A2 20090506; EP 2054515 B1 20120111; JP 2009544718 A 20091217; US 2009324554 A1 20091231
DOCDB simple family (application)
US 2007073858 W 20070719; AT 07799710 T 20070719; AU 2007275258 A 20070719; CA 2659032 A 20070719; CN 200780034953 A 20070719; EP 07799710 A 20070719; JP 2009521907 A 20070719; US 37459407 A 20070719