Global Patent Index - EP 2055789 A4

EP 2055789 A4 20091223 - PRIMER SET FOR AMPLIFICATION OF CYP2C19 GENE, REAGENT FOR AMPLIFICATION OF CYP2C19 GENE COMPRISING THE SAME, AND USE OF THE SAME

Title (en)

PRIMER SET FOR AMPLIFICATION OF CYP2C19 GENE, REAGENT FOR AMPLIFICATION OF CYP2C19 GENE COMPRISING THE SAME, AND USE OF THE SAME

Title (de)

PRIMER-SET ZUR VERSTÄRKUNG DES CYP2C19-GENS, REAGENS ZUR VERSTÄRKUNG DES CYP2C19-GENS DAMIT UND ANWENDUNG DAVON

Title (fr)

JEU D'AMORCES POUR L'AMPLIFICATION DU GÈNE CYP2C19, RÉACTIF POUR L'AMPLIFICATION DU GÈNE CYP2C19 COMPRENANT LEDIT JEU D'AMORCES ET UTILISATION DU RÉACTIF

Publication

EP 2055789 A4 20091223 (EN)

Application

EP 07832870 A 20071130

Priority

  • JP 2007073205 W 20071130
  • JP 2006322957 A 20061130
  • JP 2007232613 A 20070907

Abstract (en)

[origin: EP2055789A1] Primer sets for amplifying target regions containing sites to be detected in the CYP2C19 gene by a gene amplification method are provided, wherein the primer sets can amplify the regions specifically. Two pairs of primer sets are used including forward primers consisting of the base sequences of SEQ ID NOs: 12 and 32 as well as reverse primers consisting of the base sequences of SEQ ID NOs: 22 and 48, respectively. The use of these primer sets makes it possible to amplify two target regions including parts where two types of polymorphisms (CYP2C19*2 and CYP2C19*3) of the CYP2C19 gene are generated, respectively, in the same reaction solution at the same time.

IPC 8 full level

C12Q 1/68 (2006.01); C12N 15/09 (2006.01); C12P 19/34 (2006.01)

CPC (source: EP KR US)

C12N 15/09 (2013.01 - KR); C12P 19/34 (2013.01 - KR); C12Q 1/6844 (2013.01 - KR); C12Q 1/6876 (2013.01 - EP KR US); C12Q 1/6883 (2013.01 - EP KR US); C12Q 2527/107 (2013.01 - KR); C12Q 2600/156 (2013.01 - EP KR US)

Citation (search report)

  • [I] WO 02083839 A2 20021024 - MOTOROLA INC [US] & DATABASE Geneseq [online] 15 April 2004 (2004-04-15), XP002553658, retrieved from EBI accession no. GSN:ADI40085 Database accession no. ADI40085
  • [I] JP 2004089092 A 20040325 - SRL INC & DATABASE Geneseq [online] 1 July 2004 (2004-07-01), "Probe 4 used to detect human cytochrome P450 2C19 exon 5 point mutation.", XP002553659, retrieved from EBI accession no. GSN:ADN94992 Database accession no. ADN94992
  • [I] JP 2001017185 A 20010123 - OTSUKA PHARMA CO LTD & DATABASE Geneseq [online] 20 June 2001 (2001-06-20), XP002553660, retrieved from EBI accession no. GSN:AAF84359 Database accession no. AAF84359
  • [I] DE 10219373 A1 20040219 - ADNAGEN AG [DE]
  • [I] US 5912120 A 19990615 - GOLDSTEIN JOYCE A [US], et al
  • [A] WO 0012757 A1 20000309 - SANGTEC MEDICAL AB [SE], et al
  • [A] WO 0218639 A2 20020307 - GEMINI GENOMICS PLC [GB]
  • [A] EP 1616953 A1 20060118 - ARKRAY INC [JP]
  • [A] EP 1295941 A1 20030326 - NAT INST OF ADVANCED IND SCIEN [JP], et al
  • [I] GAIKOVITCH ELENA A ET AL: "Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population", EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, SPRINGER VERLAG, DE, vol. 59, no. 4, 1 August 2003 (2003-08-01), pages 303 - 312, XP009095053, ISSN: 0031-6970
  • See also references of WO 2008066162A1

Designated contracting state (EPC)

DE FR GB IT

DOCDB simple family (publication)

EP 2055789 A1 20090506; EP 2055789 A4 20091223; CN 102277424 A 20111214; JP WO2008066162 A1 20100311; KR 20080100429 A 20081118; US 2009269756 A1 20091029; WO 2008066162 A1 20080605

DOCDB simple family (application)

EP 07832870 A 20071130; CN 201110200006 A 20071130; JP 2007073205 W 20071130; JP 2008517253 A 20071130; KR 20087019400 A 20080807; US 30166707 A 20071130