EP 2056870 A4 20101013 - TRYPANOSOME MICROSOME SYSTEM AND USES THEREOF
Title (en)
TRYPANOSOME MICROSOME SYSTEM AND USES THEREOF
Title (de)
TRYPANOSOM-MIKROSOM-SYSTEM UND SEINE VERWENDUNGEN
Title (fr)
SYSTÈME À BASE DE MICROSOMES DE TRYPANOSOME ET SES UTILISATIONS
Publication
Application
Priority
- US 2007017555 W 20070807
- US 83604506 P 20060807
Abstract (en)
[origin: WO2008021092A2] The present invention provides cell free preparations of protozoan microsomes, wherein the cell free preparation of protozoan microsomes demonstrate the ability to translocate a protozoan polypeptide into the microsome, methods of preparing cell free preparations of protozoan microsomes, and methods of using cell free preparations of protozoan microsomes.
IPC 8 full level
A61K 39/00 (2006.01); A61K 31/00 (2006.01); G01N 33/569 (2006.01)
CPC (source: EP)
C12N 1/10 (2013.01); C12Q 1/18 (2013.01); G01N 33/56905 (2013.01); G01N 2500/00 (2013.01)
Citation (search report)
- [A] EP 1262556 A2 20021204 - FUNDACAO DE AMPARAO A PESQUISA [BR]
- [XA] VIDUGIRIENE JOLANTA ET AL: "The GPI Anchor of Cell-Surface Proteins Is Synthesized on the Cytoplasmic Face of the Endoplasmic Reticulum", JOURNAL OF CELL BIOLOGY, vol. 127, no. 2, 1994, pages 333 - 341, XP002598246, ISSN: 0021-9525
- [XA] DE LA CANAL L ET AL: "SYNTHESIS OF DOLICHOL DERIVATIVES IN TRYPANOSOMATIDS CHARACTERIZATION OF ENZYMATIC PATTERNS", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 262, no. 23, 1987, pages 11128 - 11133, XP002598247, ISSN: 0021-9258
- [X] EL MOUDNI B ET AL: "Purification and characterization of N-acetylglucosaminidase from Trypanosoma cruzi.", EXPERIMENTAL PARASITOLOGY JUL 1996 LNKD- PUBMED:8682185, vol. 83, no. 2, July 1996 (1996-07-01), pages 167 - 173, XP002598248, ISSN: 0014-4894
- [ID] AL-QAHTANI AHMED ET AL: "Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania", BIOCHEMICAL JOURNAL, vol. 331, no. 2, 15 April 1998 (1998-04-15), pages 521 - 529, XP002598249, ISSN: 0264-6021
- [T] PATHAM BHARGAVI ET AL: "Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities", BIOCHEMICAL JOURNAL, vol. 419, no. Part 2, April 2009 (2009-04-01), pages 507 - 517, XP002598250
- See references of WO 2008021092A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008021092 A2 20080221; WO 2008021092 A3 20080925; WO 2008021092 A8 20081211; CA 2660010 A1 20080221; EP 2056870 A2 20090513; EP 2056870 A4 20101013
DOCDB simple family (application)
US 2007017555 W 20070807; CA 2660010 A 20070807; EP 07811144 A 20070807