EP 2059187 A2 20090520 - USE OF NONCALCIUM ZEOLITES WITH ADDED CALCIUM SALT IN HEMOSTATIC DEVICES AND PRODUCTS
Title (en)
USE OF NONCALCIUM ZEOLITES WITH ADDED CALCIUM SALT IN HEMOSTATIC DEVICES AND PRODUCTS
Title (de)
VERWENDUNG VON NICHTCALCIUM-ZEOLITHEN MIT HINZUGEFÜGTEM CALCIUMSALZ FÜR BLUTSTILLENDE VORRICHTUNGEN UND PRODUKTE
Title (fr)
UTILISATION DE ZÉOLITES NON-CALCIQUES AVEC SEL DE CALCIUM AJOUTÉ DANS DES DISPOSITIFS HÉMOSTATIQUES, ET PRODUITS
Publication
Application
Priority
- US 2007077763 W 20070906
- US 53036906 A 20060908
Abstract (en)
[origin: WO2008030964A2] It is known that calcium exchanged zeolites are effective in hemostasis. The reason that Ca-exchanged zeolites are required has not been explained in the prior art, except that the presence of Ca<SUP>2+</SUP> ions are important in the clotting mechanism. It has now been found that the addition of Ca<SUP>2+</SUP> ions alone actually slow clotting of blood. The use of Ca-zeolites appear to be effective in hemostasis simply because they don't remove the critical Ca<SUP>2+</SUP> from the blood by ion exchange. A NaA zeolite with an effective amount of added Ca<SUP>2+</SUP> salt is nearly equally active in coagulation as the Ca-exchanged form of CaA zeolite.
IPC 8 full level
A61F 2/00 (2006.01); A61K 35/14 (2006.01); C12Q 1/56 (2006.01)
CPC (source: EP)
A61K 33/06 (2013.01); A61K 33/38 (2013.01); A61K 45/06 (2013.01)
Citation (search report)
See references of WO 2008030964A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2008030964 A2 20080313; WO 2008030964 A3 20080508; CN 101677848 A 20100324; EP 2059187 A2 20090520
DOCDB simple family (application)
US 2007077763 W 20070906; CN 200780033033 A 20070906; EP 07841971 A 20070906