EP 2063898 A1 20090603 - USE OF EQUOL FOR AMELIORATING OR PREVENTING NEUROPSYCHIATRIC AND NEURODEGENERATIVE DISEASES OR DISORDERS
Title (en)
USE OF EQUOL FOR AMELIORATING OR PREVENTING NEUROPSYCHIATRIC AND NEURODEGENERATIVE DISEASES OR DISORDERS
Title (de)
VERWENDUNG VON EQUOL ZUR LINDERUNG ODER VERHINDERUNG VON NEUROPSYCHIATRISCHEN UND NEURODEGENERATIVEN ERKRANKUNGEN ODER STÖRUNGEN
Title (fr)
UTILISATION D'ÉQUOL POUR AMÉLIORER OU PRÉVENIR DES MALADIES OU DES TROUBLES NEUROPSYCHIATRIQUES ET NEURODÉGÉNÉRATIFS
Publication
Application
Priority
US 2006032387 W 20060818
Abstract (en)
[origin: WO2008020853A1] The invention is directed to a method of preventing or ameliorating a neuropsychiatric or neurodegenerative disease or disorder in a subject. The method includes administering a composition comprising equol in an amount sufficient to prevent or ameliorate the neuropsychiatric or neurodegenerative disease or disorder. The equol may be a racemic mixture of R-equol and S-equol. The equol may be enantiomerically enriched with R-equol or enantiomerically enriched with S-equol.
IPC 8 full level
A61K 31/56 (2006.01)
CPC (source: EP)
A61K 31/56 (2013.01); A61P 3/04 (2017.12); A61P 25/00 (2017.12); A61P 25/16 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 43/00 (2017.12)
Citation (third parties)
Third party :
- US 2005245492 A1 20051103 - LEPHART EDWIN D [US], et al
- WO 9852546 A1 19981126 - GORBACH SHERWOOD L [US]
- WO 2004037327 A2 20040506 - MEDICAL HOUSE PLC [GB], et al
- WO 2005107770 A1 20051117 - TECHNOLOGY TRANSFER OFFICE [US], et al
- LUND T.D. ET AL: "Equol is a Novel Anti-Androgen that Inhibits Prostate Growth and Hormone Feedback", BIOLOGY OF REPRODUCTION, vol. 70, 2004, pages 1188 - 1195, XP003024362
- CROSIGNANI P.G. ET AL: "Polycistic ovarian disease: heritability and heterogeneity", HUMAN REPRODUCTION UPDATE, vol. 7, no. 1, 2001, pages 3 - 7, XP003024363
- JESMIN S. ET AL: "Gonadal Hormones and Frontocortical Expression of Vascular Endothelial Growth Factor in Male Stroke-Prone, Spontaneously Hypertensive Rats, a Model for Attention- Deficit/Hyperactivity Disorder", ENDOCRINOLOGY, vol. 145, no. 9, 2004, pages 4330 - 4343, XP003024364
- EXCIPIENT: "Standard Dictionary of the English Language", 1974, FUNK & WAGNALL'S, NEW YORK, pages: 443, XP003024365
- LEPHART E.D. ET AL: "Behavioral Effects of Endocrine-disrupting Substances: Phytoestrogens", ILAR JOURNAL, vol. 45, no. 4, 2004, pages 443 - 454, XP003024366
- MUTHYALA R.S. ET AL: "Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S- equols and their differing binding and biological activity through estrogen receptors alpha and beta", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 12, no. 6, 2004, pages 1559 - 1567, XP003024367
- MORITO K. ET AL: "Interaction of Phystoestrogens with Estrogen Receptors Alpha and Beta", BIOL. PHARM. BULL., vol. 24, no. 4, 2001, pages 351 - 356, XP003024368
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2008020853 A1 20080221; AU 2006347276 A1 20080221; AU 2006347276 B2 20121129; CA 2660056 A1 20080221; EP 2063898 A1 20090603; EP 2063898 A4 20120215; JP 2010501485 A 20100121
DOCDB simple family (application)
US 2006032387 W 20060818; AU 2006347276 A 20060818; CA 2660056 A 20060818; EP 06813546 A 20060818; JP 2009524589 A 20060818