Global Patent Index - EP 2068877 A4

EP 2068877 A4 20110921 - COMPOUNDS AND METHODS OF MODULATING ANGIOGENESIS

Title (en)

COMPOUNDS AND METHODS OF MODULATING ANGIOGENESIS

Title (de)

VERBINDUNGEN UND VERFAHREN ZUR MODULIERUNG VON ANGIOGENESE

Title (fr)

COMPOSÉS ET MÉTHODES DE MODULATION DE L'ANGIOGENÈSE

Publication

EP 2068877 A4 20110921 (EN)

Application

EP 07840438 A 20070719

Priority

  • US 2007073877 W 20070719
  • US 83199206 P 20060719

Abstract (en)

[origin: WO2008011513A2] A method of modulating angiogenesis in a tissue comprises administering to the tissue a therapeutically effective amount of an agent that modulates complex formation of a<SUB>v</SUB>ß<SUB>3</SUB> integrin and VEGFR2.

IPC 8 full level

A61K 38/04 (2006.01); A61K 31/47 (2006.01); A61K 38/08 (2019.01); A61K 38/17 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01); C07D 215/16 (2006.01); C07D 215/20 (2006.01)

CPC (source: EP US)

A61K 38/04 (2013.01 - EP); A61K 38/08 (2013.01 - EP US); A61K 38/17 (2013.01 - EP); A61P 27/02 (2017.12 - EP); A61P 35/00 (2017.12 - EP)

Citation (search report)

  • [X] WO 9816241 A1 19980423 - UNIV VANDERBILT [US], et al
  • [X] WO 9822500 A2 19980528 - COR THERAPEUTICS INC [US]
  • [X] WO 0179144 A2 20011025 - COR THERAPEUTICS INC [US], et al
  • [X] FRIEDLANDER MARTIN ET AL: "Involvement of integrins, alpha-v-beta-3 and alpha-v-beta-5 in ocular neovascular diseases", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, no. 18, 1996, pages 9764 - 9769, XP000986063, ISSN: 0027-8424
  • [A] MAHABALESHWAR GANAPATI H ET AL: "Beta 3 integrin phosphorylation and VEGF signaling", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 106, no. 11, Part 1, 1 November 2005 (2005-11-01), pages 159A, XP009151001, ISSN: 0006-4971
  • [A] SOLDI RAFFAELLA ET AL: "Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, vol. 18, no. 4, 15 February 1999 (1999-02-15), pages 882 - 892, XP002656146, ISSN: 0261-4189
  • See references of WO 2008011513A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2008011513 A2 20080124; WO 2008011513 A3 20080814; WO 2008011513 B1 20081016; EP 2068877 A2 20090617; EP 2068877 A4 20110921

DOCDB simple family (application)

US 2007073877 W 20070719; EP 07840438 A 20070719