EP 2070521 A1 20090617 - Surface-modified nanoparticles

Title (en)

Surface-modified nanoparticles

Title (de)

Nanopartikel mit modifizierter Oberfläche

Title (fr)

Nanoparticules à surface modifiée

Publication

EP 2070521 A1 20090617 (EN)

Application

EP 07076065 A 20071210

Priority

EP 07076065 A 20071210

Abstract (en)

The present invention relates to compositions of drug-bearing nanoparticles having a modified surface, pharmaceutical kits containing the individual components of said compositions, the medical uses thereof, as well as a method for producing said compositions.

IPC 8 full level

A61K 9/51 (2006.01); A61K 31/427 (2006.01)

CPC (source: EP)

A61K 9/5153 (2013.01); A61K 9/5192 (2013.01); A61K 31/427 (2013.01); A61P 35/00 (2017.12)

Citation (applicant)

WO 9522963 A1 19950831 - MEDINOVA MED CONSULTING GMBH [DE]
WO 03094894 A1 20031120 - ELAN PHARMA INT LTD [IE], et al
US 6288040 B1 20010911 - MUELLER RANIER H [DE], et al
WO 2005110407 A2 20051124 - BRISTOL MYERS SQUIBB CO [US], et al
WO 9310102 A1 19930527 - CENTRE NAT RECH SCIENT [FR]
WO 9310121 A1 19930527 - BIOTECHNOLOG FORSCHUNG GMBH [DE], et al
DE 4138042 A1 19930527 - BIOTECHNOLOG FORSCHUNG GMBH [DE]
WO 9719086 A1 19970529 - BIOTECHNOLOG FORSCHUNG GMBH [DE], et al
WO 9825929 A1 19980618 - CIBA GEIGY AG [CH], et al
WO 9943320 A1 19990902 - NOVARTIS AG [CH], et al
WO 0066589 A1 20001109 - SCHERING AG [US], et al
WO 0049021 A2 20000824 - SCHERING AG [DE], et al
WO 0071521 A1 20001130 - BRISTOL MYERS SQUIBB CO [US]
WO 0127308 A2 20010419 - NOVARTIS AG [CH], et al
WO 9902514 A2 19990121 - BRISTOL MYERS SQUIBB CO [US]
WO 02080846 A2 20021017 - KOSAN BIOSCIENCES INC [US]
DE 19907588 A1 20000824 - BIOTECHNOLOG FORSCHUNG GMBH [DE]
WO 9958534 A2 19991118 - BIOTECHNOLOG FORSCHUNG GMBH [DE], et al
WO 9902514 A2 19990121 - BRISTOL MYERS SQUIBB CO [US]
WO 9967252 A2 19991229 - NOVARTIS AG [CH], et al
WO 9967253 A2 19991229 - NOVARTIS AG [CH], et al
WO 9907692 A2 19990218 - SCHERING AG [DE], et al
EP 0994915 A1 20000426 - BASF AG [DE]
WO 0001333 A2 20000113 - SCA HYGIENE PROD AB [SE], et al
WO 0066589 A1 20001109 - SCHERING AG [US], et al
WO 0049019 A2 20000824 - SCHERING AG [DE], et al
WO 0049020 A2 20000824 - SCHERING AG [DE], et al
WO 0037473 A1 20000629 - NOVARTIS AG [CH], et al
WO 0057874 A1 20001005 - BRISTOL MYERS SQUIBB CO [US]
WO 0192255 A2 20011206 - KOSAN BIOSCIENCES INC [US], et al
WO 0181342 A2 20011101 - SCHERING AG [DE], et al
WO 0173103 A2 20011004 - BRISTOL MYERS SQUIBB CO [US], et al
WO 0164650 A2 20010907 - SLOAN KETTERING INST CANCER [US], et al
WO 0170716 A1 20010927 - BRISTOL MYERS SQUIBB CO [US], et al
US 6204388 B1 20010320 - DANISHEFSKY SAMUEL J [US], et al
US 6387927 B1 20020514 - ALTMANN KARL-HEINZ [CH], et al
US 6380394 B1 20020430 - NICOLAOU KYRIACOS C [US], et al
US 252028 A 18820110
US 258286 A 18820523
US 262030 A 18820801
WO 0232844 A2 20020425 - MORPHOCHEM AG [DE], et al
WO 0230356 A2 20020418 - UNIV MISSISSIPI [US]
WO 0214323 A2 20020221 - BRISTOL MYERS SQUIBB CO [US], et al
WO 0208440 A2 20020131 - KOSAN BIOSCIENCES INC [US]
LUDUVICO, I. ET AL., MINI-REVIEWS IN ORGANIC CHEMISTRY, vol. 3, 2006, pages 49 - 75
BALOG, D. M. ET AL., ANGEW. CHEM., vol. 108, 1996, pages 2976
SU, D.-S. ET AL., ANGEW. CHEM. INT. ED. ENGL., vol. 36, 1997, pages 757
YANG, Z. ET AL., ANGEW. CHEM. INT. ED. ENGL., vol. 36, 1997, pages 166
SCHINZER, D. ET AL., ANGEW. CHEM. INT. ED. ENGL., vol. 36, 1997, pages 523
MULZER, J.; MANTOULIDIS, A.; ÖHLER, E., J. ORG. CHEM., vol. 65, 2000, pages 7456 - 7467
BODE, J. W.; CARREIRA, E. M., J. AM. CHEM. SOC., vol. 123, 2001, pages 3611 - 3612
YEZHELYEV, M. V. ET AL., THE LANCET ONCOLOGY, vol. 7, 2006, pages 657 - 667
LIESKE, A; JAEGER, W., MACROMOL. CHEM. PHYS., vol. 199, 1998, pages 255 - 260

Citation (search report)

[X] WO 9918934 A1 19990422 - UNIV VANDERBILT [US]
[X] WO 2007025767 A2 20070308 - SCHERING AG [DE], et al
[X] YANG S C ET AL: "Formation of positively charged poly(butyl cyanoacrylate) nanoparticles stabilized with chitosan", COLLOID & POLYMER SCIENCE, SPRINGER VERLAG, HEIDELBERG, DE, vol. 278, no. 4, 1 January 2000 (2000-01-01), pages 285 - 292, XP002481607, ISSN: 0303-402X

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK RS

DOCDB simple family (publication)

EP 2070521 A1 20090617; AR 069639 A1 20100210; PA 8807001 A1 20090723; PE 20091271 A1 20090920; TW 200932287 A 20090801; UY 31522 A1 20090803; WO 2009074233 A1 20090618

DOCDB simple family (application)

EP 07076065 A 20071210; AR P080105367 A 20081210; EP 2008010104 W 20081128; PA 8807001 A 20081210; PE 2008002040 A 20081210; TW 97147677 A 20081208; UY 31522 A 20081210