EP 2091917 A1 20090826 - ION CHANNEL MODULATORS
Title (en)
ION CHANNEL MODULATORS
Title (de)
IONENKANALMODULATOREN
Title (fr)
MODULATEURS DE CANAUX IONIQUES
Publication
Application
Priority
- US 2007087073 W 20071211
- US 87417806 P 20061211
Abstract (en)
[origin: WO2008073934A1] The present teachings provide compounds of Formula (I) and pharmaceutically acceptable salts, hydrates, and esters thereof, wherein Ar, R<SUP>1</SUP>, R<SUP>1'</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP> R<SUP>4'</SUP>, and p are defined herein. The present teachings also provide processes for producing said compounds and their pharmaceutically acceptable salts, hydrates and esters, and methods of treating a pathological condition or disorder, or alleviating a symptom thereof, using said compounds including their pharmaceutically acceptable salts, hydrates and esters. The compounds can be useful in modulating ion channel activity including treating a variety of conditions associated with the abnormal modulation of one or more voltage-gated calcium channels.
IPC 8 full level
C07D 213/36 (2006.01); A61K 31/426 (2006.01); A61K 31/435 (2006.01); A61P 9/00 (2006.01); C07D 213/74 (2006.01); C07D 277/42 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/06 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); C07D 213/36 (2013.01); C07D 213/74 (2013.01); C07D 277/42 (2013.01)
Citation (search report)
See references of WO 2008073934A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008073934 A1 20080619; CA 2672236 A1 20080619; EP 2091917 A1 20090826; JP 2010512417 A 20100422; MX 2009006233 A 20090622
DOCDB simple family (application)
US 2007087073 W 20071211; CA 2672236 A 20071211; EP 07865491 A 20071211; JP 2009541516 A 20071211; MX 2009006233 A 20071211