EP 2091969 A2 20090826 - POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS
Title (en)
POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS
Title (de)
POLYPEPTIDE MIT VERBESSERTEN ENTZÜNDUNGSHEMMENDEN UND VERMINDERTEN ZYTOTOXISCHEN EIGENSCHAFTEN UND DAMIT IM ZUSAMMENHANG STEHENDE VERFAHREN
Title (fr)
POLYPEPTIDES AYANT DES PROPRIETES ANTIINFLAMMATOIRES ACCRUES ET CYTOTOXIQUES REDUITES ET PROCEDES ASSOCIES
Publication
Application
Priority
- US 2007072771 W 20070703
- US 2006041791 W 20061027
- US 2007008396 W 20070403
Abstract (en)
[origin: WO2008057634A2] The invention provides a polypeptide containing at least one IgG Fc region, wherein said at least one IgG Fc region is glycosylated with at least one galactose moiety connected to a respective terminal sialic acid moiety by a a 2, 6 linkage, and wherein said polypeptide having a higher anti-inflammatory activity as compared to an unpurified antibody.
IPC 8 full level
C07K 16/00 (2006.01); A61K 39/395 (2006.01); C07K 1/00 (2006.01); C12P 21/08 (2006.01)
CPC (source: EP)
C07K 16/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/71 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008057634 A2 20080515; WO 2008057634 A3 20081204; AU 2007317755 A1 20080515; EP 2091969 A2 20090826; EP 2091969 A4 20100512
DOCDB simple family (application)
US 2007072771 W 20070703; AU 2007317755 A 20070703; EP 07812601 A 20070703